Tecfidera and Altace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tecfidera (dimethyl fumarate) and Altace (ramipril). Common drug interactions include flushing among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Tecfidera and Altace. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

What is Altace?

Altace has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 23,681 Altace users. Check the latest studies of Altace.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

32 people who take Tecfidera and Altace together, and have interactions are studied.

Tecfidera and Altace drug interactions.

What are the common drug interactions of Tecfidera and Altace, by gender? *:

female:

  1. Flushing (the warm, red condition of human skin)
  2. Fatigue (feeling of tiredness)
  3. Nausea (feeling of having an urge to vomit)
  4. Pruritus (severe itching of the skin)
  5. Hepatic enzyme increased
  6. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  7. Urinary tract infection
  8. Flatulence (flatus expelled through the anus)
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  10. Hot flush (sudden feelings of heat)

male:

  1. Anxiety
  2. Drug ineffective
  3. Dysarthria (speech disorder)
  4. Dyspnoea (difficult or laboured respiration)
  5. Gait disturbance
  6. Hemiplegia (paralysis of one side of the body)
  7. Loss of consciousness
  8. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  9. Muscle strain (an injury to a muscle in which the muscle fibres tear)
  10. Muscular weakness (muscle weakness)

What are the common drug interactions of Tecfidera and Altace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Blood pressure decreased
  3. Fall
  4. Fatigue (feeling of tiredness)
  5. Flatulence (flatus expelled through the anus)
  6. Flushing (the warm, red condition of human skin)
  7. Fungal infection
  8. Gastric disorder (disease of stomach)
  9. Influenza like illness
  10. Injection site pain

50-59:

  1. Flushing (the warm, red condition of human skin)
  2. Hepatic enzyme increased
  3. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  4. Hot flush (sudden feelings of heat)
  5. Urticaria (rash of round, red welts on the skin that itch intensely)
  6. Diarrhoea
  7. Aggression
  8. Angioedema (rapid swelling of the dermis)
  9. Anxiety
  10. Arthralgia (joint pain)

60+:

  1. Urinary tract infection
  2. Fatigue (feeling of tiredness)
  3. Swelling face
  4. Upper limb fracture
  5. Anaemia (lack of blood)
  6. Anxiety
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Chest discomfort
  9. Depressed mood
  10. Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

  1. Gait Disturbance: 5 people, 15.62%

* Approximation only. Some reports may have incomplete information.

Do you take Tecfidera and Altace?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tecfidera and Altace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tecfidera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Altace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tecfidera and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Altace and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dimethyl fumarate and ramipril (the active ingredients of Tecfidera and Altace, respectively), and Tecfidera and Altace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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