Tecfidera and Asacol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tecfidera (dimethyl fumarate) and Asacol (mesalamine). Common drug interactions include road traffic accident among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Tecfidera and Asacol. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

What is Asacol?

Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.

On Jul, 06, 2026

12 people who take Tecfidera and Asacol together, and have interactions are studied.

What are the common drug interactions of Tecfidera and Asacol, by gender? *:

female:

Road traffic accident
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colon injury
Dyspnoea (difficult or laboured respiration)
Oxygen saturation decreased
Pain
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)

male:

Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal discomfort
Abdominal pain upper
Diarrhoea
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Pyrexia (fever)
Acute myocardial infarction (acute heart attack)
Photosensitivity reaction

What are the common drug interactions of Tecfidera and Asacol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Road traffic accident
Bipolar disorder (mood disorder)
Overdose
Suicide attempt

40-49:

Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

50-59:

Diarrhoea
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Vomiting
Cardiac failure
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Abdominal discomfort

60+:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colon injury
Dyspnoea (difficult or laboured respiration)
Oxygen saturation decreased
Pain
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Nausea (feeling of having an urge to vomit)
Vomiting

What are the existing conditions these people have? *

Pain: 1 person, 8.33%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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