Tecfidera and Glucagon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tecfidera (dimethyl fumarate) and Glucagon (glucagon hydrochloride). Common drug interactions include diabetic retinopathy among females and blood pressure decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Tecfidera and Glucagon. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

What is Glucagon?

Glucagon has active ingredients of glucagon hydrochloride. eHealthMe is studying from 4,297 Glucagon users. Check the latest studies of Glucagon.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

41 people who take Tecfidera and Glucagon together, and have interactions are studied.

Tecfidera and Glucagon drug interactions.

What are the common drug interactions of Tecfidera and Glucagon, by gender? *:

female:

Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Fatigue (feeling of tiredness)
Diabetes mellitus inadequate control
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Headache (pain in head)
Lymphocyte count decreased
Alanine aminotransferase increased
Cataract subcapsular (cataracts that affect the back of the lens)
Cystoid macular oedema (fluid accumulation after cataract surgery)
Dizziness

male:

Blood pressure decreased
Dehydration (dryness resulting from the removal of water)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nausea (feeling of having an urge to vomit)
Pain
Vomiting
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)

What are the common drug interactions of Tecfidera and Glucagon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Anaemia (lack of blood)
Haemoglobin decreased
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Intraocular pressure increased
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection

40-49:

Fatigue (feeling of tiredness)
Alanine aminotransferase increased
Cataract subcapsular (cataracts that affect the back of the lens)
Cystoid macular oedema (fluid accumulation after cataract surgery)
Diabetes mellitus inadequate control
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dizziness
Episcleritis (acute inflammatory disorder of the episclera of eye)
Eye pain
Gamma-glutamyltransferase increased

50-59:

Abdominal pain
Death
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Cholecystitis (infection of gallbladder)
Drug ineffective
General symptom
Pancreatitis (inflammation of pancreas)
Surgery

60+:

Hypotension (abnormally low blood pressure)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Adverse drug reaction
Cholecystitis acute (rapid infection of gallbladder)
Constipation
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Immune thrombocytopenic purpura (destruction of blood platelets due to the presence of antiplatelet auto antibodies)
Platelet count decreased
White blood cell count decreased

What are the existing conditions these people have? *

Diabetes Mellitus Inadequate Control: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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