Tecfidera and Strattera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tecfidera (dimethyl fumarate) and Strattera (atomoxetine hydrochloride). Common drug interactions include flushing among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Tecfidera and Strattera. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

What is Strattera?

Strattera has active ingredients of atomoxetine hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,324 Strattera users. Check the latest studies of Strattera.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

34 people who take Tecfidera and Strattera together, and have interactions are studied.

Tecfidera and Strattera drug interactions.

What are the common drug interactions of Tecfidera and Strattera, by gender? *:

female:

Flushing (the warm, red condition of human skin)
Drug ineffective
Respiratory failure (inadequate gas exchange by the respiratory system)
Gait disturbance
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Nausea (feeling of having an urge to vomit)
Feeling hot
Pruritus (severe itching of the skin)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Hemiparesis (weakness on one side of the body)

male:

Flushing (the warm, red condition of human skin)
Fatigue (feeling of tiredness)
Memory impairment
Urinary retention (the inability to completely or partially empty the bladder)
Visual impairment
Chest pain
Lymphocyte count decreased
Cardiac disorder
Bladder disorder
Constipation

What are the common drug interactions of Tecfidera and Strattera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug ineffective
Respiratory failure (inadequate gas exchange by the respiratory system)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Gait disturbance
Hemiparesis (weakness on one side of the body)
Flushing (the warm, red condition of human skin)
Miliaria (a skin disease marked by small and itchy rashes)
Nausea (feeling of having an urge to vomit)

30-39:

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Abdominal pain upper
Blood pressure decreased
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Diarrhoea
Haematochezia (passage of stools containing blood)
Maternal exposure during pregnancy (use of substance during pregnancy)
Vasculitis (inflammation of a blood vessel or blood vessels)

40-49:

Flushing (the warm, red condition of human skin)
Alopecia (absence of hair from areas of the body)
Erythema (redness of the skin)
Feeling hot
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Stomatitis (inflammation of mucous membrane of mouth)
Nausea (feeling of having an urge to vomit)
Abasia (inability to walk)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)

50-59:

Flushing (the warm, red condition of human skin)
Fall
Pruritus (severe itching of the skin)
Rash macular (small, flat red spots)
Vomiting
Abdominal pain upper
Breast cancer
Diarrhoea
White blood cell count decreased
Bladder disorder

60+:

n/a

What are the existing conditions these people have? *

Headache (pain in head): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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