Tegretol and Doxil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tegretol (carbamazepine) and Doxil (doxorubicin hydrochloride). Common drug interactions include balance disorder among females and bursitis among males.
The phase IV clinical study analyzes what interactions people have when they take Tegretol and Doxil. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Tegretol?
Tegretol has active ingredients of carbamazepine. It is often used in epilepsy. eHealthMe is studying from 45,969 Tegretol users. Check the latest studies of Tegretol.
What is Doxil?
Doxil has active ingredients of doxorubicin hydrochloride. It is often used in ovarian cancer. eHealthMe is studying from 10,479 Doxil users. Check the latest studies of Doxil.
23 people who take Tegretol and Doxil together, and have interactions are studied.

What are the common drug interactions of Tegretol and Doxil, by gender? *:
female:
- Balance disorder
- Bone disorder
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
- Decreased appetite
- Diarrhoea
- Dysphagia (a condition in which swallowing is difficult or painful)
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Fall
- Fatigue (feeling of tiredness)
- Fistula (an abnormal connection or passageway between two)
male:
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
- Atrioventricular block first degree (heart block first degree)
- Back pain
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Bone disorder
- Bone loss
- Bradycardia (abnormally slow heart action)
- Cardiac murmur (an heart sound in valve abnormality)
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
What are the common drug interactions of Tegretol and Doxil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abdominal pain
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anxiety
- Aortic arteriosclerosis (hardening of the aortic arteries)
- Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Asthenia (weakness)
- Atrioventricular block first degree (heart block first degree)
- Back pain
40-49:
- Abdominal pain
- Anaemia (lack of blood)
- Hypertension (high blood pressure)
- Nausea (feeling of having an urge to vomit)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pleural effusion (water on the lungs)
- Renal failure (kidney dysfunction)
- Vomiting
- Sepsis (a severe blood infection that can lead to organ failure and death)
50-59:
- Bone disorder
- Intervertebral disc degeneration (spinal disc degeneration)
- Osteonecrosis of jaw (death of bone of jaw)
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
- Decreased appetite
- Diarrhoea
- Dysphagia (a condition in which swallowing is difficult or painful)
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Fall
- Fatigue (feeling of tiredness)
60+:
- Alopecia (absence of hair from areas of the body)
- Hair colour changes
- Hair disorder
- Neutropenia (an abnormally low number of neutrophils)
- Thrombocytopenia (decrease of platelets in blood)
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
- Renal failure acute (rapid kidney dysfunction)
What are the existing conditions these people have? *
- Breast Cancer: 12 people, 52.17%
- Pain: 11 people, 47.83%
- Metastases To Bone (cancer spreads to bone): 11 people, 47.83%
- High Blood Pressure: 11 people, 47.83%
- Bone Pain: 11 people, 47.83%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 11 people, 47.83%
- Constipation: 9 people, 39.13%
- Multiple Myeloma (cancer of the plasma cells): 4 people, 17.39%
- Ovarian Cancer (cancer of ovary): 3 people, 13.04%
- Breast Cancer Metastatic: 2 people, 8.70%
* Approximation only. Some reports may have incomplete information.
Do you take Tegretol and Doxil?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tegretol and Doxil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tegretol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Doxil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tegretol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Doxil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
- Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
- Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .
- Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
- Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
- Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carbamazepine and doxorubicin hydrochloride (the active ingredients of Tegretol and Doxil, respectively), and Tegretol and Doxil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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