Tegretol and Mexitil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tegretol (carbamazepine) and Mexitil (mexiletine hydrochloride). Common drug interactions include erythema among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Tegretol and Mexitil. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Tegretol?

Tegretol has active ingredients of carbamazepine. It is often used in epilepsy. eHealthMe is studying from 45,969 Tegretol users. Check the latest studies of Tegretol.

What is Mexitil?

Mexitil has active ingredients of mexiletine hydrochloride. eHealthMe is studying from 1,893 Mexitil users. Check the latest studies of Mexitil.

On Aug, 03, 2026

79 people who take Tegretol and Mexitil together, and have interactions are studied.

What are the common drug interactions of Tegretol and Mexitil, by gender? *:

female:

Erythema (redness of the skin)
Pyrexia (fever)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Drug eruption (adverse drug reaction of the skin)
Acidosis (build-up of carbon dioxide in the blood)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Ascites (accumulation of fluid in the abdominal cavity)
Colonic perforation (a hole in the colon)
Eosinophil count increased
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)

male:

Pyrexia (fever)
Clavicle fracture
Blood alkaline phosphatase increased
Blood lactate dehydrogenase increased
C-reactive protein increased
Diarrhoea
Erythema (redness of the skin)
Gamma-glutamyltransferase increased
Lymphocyte stimulation test positive
Alanine aminotransferase increased

What are the common drug interactions of Tegretol and Mexitil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Acidosis (build-up of carbon dioxide in the blood)
Ascites (accumulation of fluid in the abdominal cavity)
Colonic perforation (a hole in the colon)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Drug ineffective
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Oliguria (not enough urine)
Sepsis (a severe blood infection that can lead to organ failure and death)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Abdominal distension

30-39:

Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Drug eruption (adverse drug reaction of the skin)
Pyrexia (fever)
Anaemia (lack of blood)
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Erythema (redness of the skin)
Generalised oedema (swelling all over the body)
Haematochezia (passage of stools containing blood)

40-49:

Pyrexia (fever)
Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Rash generalised (rash on most of body parts)
Blood lactate dehydrogenase increased
C-reactive protein increased
Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood alkaline phosphatase increased
Cytomegalovirus test positive

50-59:

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nasopharyngitis (inflammation of the nasopharynx)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Hepatic steatosis (fatty liver disease)
Alcohol interaction
Dizziness
Road traffic accident
Anaemia (lack of blood)
Pleural effusion (water on the lungs)
Pyrexia (fever)

60+:

Pyrexia (fever)
Rash
Blood alkaline phosphatase increased
Encephalitis (inflammation of the brain)
Gamma-glutamyltransferase increased
Generalised oedema (swelling all over the body)
Anaemia (lack of blood)
Blood creatinine increased
Blood glucose increased
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)

What are the existing conditions these people have? *

Pain: 14 people, 17.72%
Nerve Injury: 11 people, 13.92%
Neuralgia (pain in one or more nerves): 9 people, 11.39%
Depression: 9 people, 11.39%
High Blood Pressure: 7 people, 8.86%
Insomnia (sleeplessness): 5 people, 6.33%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 6.33%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 5 people, 6.33%
Gastric Ulcer (stomach ulcer): 5 people, 6.33%
Hypoaesthesia (reduced sense of touch or sensation): 5 people, 6.33%

* Approximation only. Some reports may have incomplete information.

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