Tekturna and Centrum drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tekturna (aliskiren hemifumarate) and Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include abdominal discomfort among females and insomnia among males.
The phase IV clinical study analyzes what interactions people have when they take Tekturna and Centrum. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.
What is Tekturna?
Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.
What is Centrum?
Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.
71 people who take Tekturna and Centrum together, and have interactions are studied.

What are the common drug interactions of Tekturna and Centrum, by gender? *:
female:
- Abdominal discomfort
- Appetite disorder (abnormal eating habits)
- Flatulence (flatus expelled through the anus)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Gait disturbance
- Head injury
- Loss of consciousness
- Malaise (a feeling of general discomfort or uneasiness)
- Adverse drug reaction
- Anaemia (lack of blood)
male:
- Insomnia (sleeplessness)
- Dyspnoea (difficult or laboured respiration)
- Asthma
- Chronic kidney disease
- Flushing (the warm, red condition of human skin)
- Hypotension (abnormally low blood pressure)
- Vomiting
- Hepatic steatosis (fatty liver disease)
- Hyperhidrosis (abnormally increased sweating)
- Acute pulmonary oedema (sudden deposit of fluid in the lung))
What are the common drug interactions of Tekturna and Centrum, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Asthma
- Cough
- Dyspnoea (difficult or laboured respiration)
- Lung abscess (pus in lungs)
- Productive cough
- Streptococcus test positive
- Tooth disorder (tooth disease)
60+:
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Nasopharyngitis (inflammation of the nasopharynx)
- Nausea (feeling of having an urge to vomit)
- Pruritus (severe itching of the skin)
- Type 2 diabetes mellitus
- Wheezing (a high-pitched whistling sound made while you breath)
- Diarrhoea
- Acute myocardial infarction (acute heart attack)
- Drug effect decreased
What are the existing conditions these people have? *
- High Blood Cholesterol: 10 people, 14.08%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 12.68%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 9 people, 12.68%
- Pain: 6 people, 8.45%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.45%
- Diabetes: 6 people, 8.45%
- Stress And Anxiety: 5 people, 7.04%
- Cardiac Disorder: 5 people, 7.04%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 5.63%
- Psoriasis (immune-mediated disease that affects the skin): 4 people, 5.63%
* Approximation only. Some reports may have incomplete information.
Do you take Tekturna and Centrum?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tekturna and Centrum:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tekturna:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Centrum:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tekturna and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Centrum and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on aliskiren hemifumarate and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Tekturna and Centrum, respectively), and Tekturna and Centrum (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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