Tekturna and Phenergan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tekturna (aliskiren hemifumarate) and Phenergan (promethazine hydrochloride). Common drug interactions include dizziness among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Tekturna and Phenergan. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Tekturna?

Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 25,312 Phenergan users. Check the latest studies of Phenergan.



On Jul, 18, 2026

13 people who take Tekturna and Phenergan together, and have interactions are studied.

Tekturna and Phenergan drug interactions.

What are the common drug interactions of Tekturna and Phenergan, by gender? *:

female:

  1. Dizziness
  2. Epistaxis (bleed from the nose)
  3. Fall
  4. Gait disturbance
  5. Abdominal discomfort
  6. Alopecia (absence of hair from areas of the body)
  7. Anaemia (lack of blood)
  8. Angioedema (rapid swelling of the dermis)
  9. Blood pressure decreased
  10. Burning sensation

male:

  1. Cardiac failure congestive
  2. Constipation
  3. Asthenia (weakness)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Back pain
  6. Blood glucose increased
  7. Decreased appetite
  8. Drug ineffective
  9. Dyspnoea (difficult or laboured respiration)
  10. Dysuria (painful or difficult urination)

What are the common drug interactions of Tekturna and Phenergan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Constipation
  2. Dizziness
  3. Fall
  4. Pleural effusion (water on the lungs)
  5. Sinus headache (headache caused by sinus infections)

60+:

  1. Cardiac failure congestive
  2. Dizziness
  3. Arteriosclerosis (thickening and hardening of arteries)
  4. Arthralgia (joint pain)
  5. Asthenia (weakness)
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Back pain
  8. Blood glucose increased
  9. Blood pressure decreased
  10. Burning sensation

What are the existing conditions these people have? *

  1. Insomnia (sleeplessness): 2 people, 15.38%
  2. Stress And Anxiety: 1 person, 7.69%
  3. Hypersensitivity: 1 person, 7.69%
  4. Breast Cancer Female: 1 person, 7.69%
  5. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 7.69%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
  7. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 7.69%
  8. High Blood Cholesterol: 1 person, 7.69%
  9. Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 1 person, 7.69%
  10. Impaired Gastric Emptying: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Tekturna and Phenergan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tekturna and Phenergan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tekturna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Phenergan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tekturna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Phenergan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on aliskiren hemifumarate and promethazine hydrochloride (the active ingredients of Tekturna and Phenergan, respectively), and Tekturna and Phenergan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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