Telmisartan and Sinemet drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Telmisartan (telmisartan) and Sinemet (carbidopa; levodopa). Common drug interactions include asthenia among females and aggression among males.
The phase IV clinical study analyzes what interactions people have when they take Telmisartan and Sinemet. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Telmisartan?
Telmisartan has active ingredients of telmisartan. It is often used in high blood pressure. eHealthMe is studying from 9,163 Telmisartan users. Check the latest studies of Telmisartan.
What is Sinemet?
Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.
15 people who take Telmisartan and Sinemet together, and have interactions are studied.

What are the common drug interactions of Telmisartan and Sinemet, by gender? *:
female:
- Asthenia (weakness)
- Lymphocyte count decreased
- Asthma
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Chest discomfort
- Cough
- Dyspnoea (difficult or laboured respiration)
- Panic attack
- Productive cough
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
male:
- Aggression
- Balance disorder
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Death
- Delusion (a false belief or opinion)
- Dementia (madness)
- Drug ineffective
- Hallucination (an experience involving the perception of something not present)
- Mobility decreased (ability to move is reduced)
What are the common drug interactions of Telmisartan and Sinemet, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Increased upper airway secretion
- Panic attack
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
- Productive cough
- Psychotic disorder
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
- Victim of abuse
- Wheezing (a high-pitched whistling sound made while you breath)
- Adrenal mass
60+:
- Anxiety
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Dyspnoea (difficult or laboured respiration)
- Panic attack
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Productive cough
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
- Alopecia (absence of hair from areas of the body)
- Anaemia (lack of blood)
- Apraxia (disorder that affects a person's ability to organize the movements of the muscles used in speech)
What are the existing conditions these people have? *
- Cardiac Disorder: 2 people, 13.33%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 13.33%
- Asthma: 2 people, 13.33%
- Type 2 Diabetes: 1 person, 6.67%
- Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 1 person, 6.67%
- Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 1 person, 6.67%
- Bladder Disorder: 1 person, 6.67%
- Blood Glucose Abnormal: 1 person, 6.67%
- Blood Pressure Abnormal: 1 person, 6.67%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Telmisartan and Sinemet?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Telmisartan (9,163 reports)
- Sinemet (29,601 reports)
Browse all drug interactions of Telmisartan and Sinemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Telmisartan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sinemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Telmisartan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sinemet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Kato Y, Mukai Y, Rane A, Inotsume N, Toda T, "The inhibitory effect of telmisartan on the metabolism of arachidonic acid by CYP2C9 and CYP2C8: an in vitro study", Biological and Pharmaceutical Bulletin, 2017 Sep .
- Kim HK, Youm JB, Lee SR, Lim SE, Lee SY, Ko TH, Nilius B, Noh JH, Ko KS, Rhee BD, Kim N, "The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action", Pflügers Archiv-European Journal of Physiology, 2012 Dec .
- Kato Y, Mukai Y, Rane A, Inotsume N, Toda T, "The inhibitory effect of telmisartan on the metabolism of arachidonic acid by CYP2C9 and CYP2C8: an in vitro study", Biological and Pharmaceutical Bulletin, 2017 Sep .
- Kim HK, Youm JB, Lee SR, Lim SE, Lee SY, Ko TH, Nilius B, Noh JH, Ko KS, Rhee BD, Kim N, "The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action", Pflügers Archiv-European Journal of Physiology, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on telmisartan and carbidopa; levodopa (the active ingredients of Telmisartan and Sinemet, respectively), and Telmisartan and Sinemet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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