Temaz and Durezol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Temaz (temazepam) and Durezol (difluprednate). Common drug interactions include vitreous haemorrhage among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Temaz and Durezol. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Temaz?

Temaz has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 42,293 Temaz users. Check the latest studies of Temaz.

What is Durezol?

Durezol has active ingredients of difluprednate. It is often used in uveitis. eHealthMe is studying from 3,441 Durezol users. Check the latest studies of Durezol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

21 people who take Temaz and Durezol together, and have interactions are studied.

What are the common drug interactions of Temaz and Durezol, by gender? *:

female:

Vitreous haemorrhage (intraocular (inside the eye) bleeding)
Arthritis enteropathic (form of chronic, inflammatory arthritis associated with the occurrence of an inflammatory bowel disease)
Blindness
Chronic kidney disease
Bone pain
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug ineffective
Eye pain

male:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Deafness unilateral
Dental discomfort
Diarrhoea haemorrhagic (bloody diarrhoea)
Dizziness
Dry mouth
Dyspnoea (difficult or laboured respiration)
Epistaxis (bleed from the nose)
Eye disorder

What are the common drug interactions of Temaz and Durezol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Arthritis enteropathic (form of chronic, inflammatory arthritis associated with the occurrence of an inflammatory bowel disease)

20-29:

Diarrhoea haemorrhagic (bloody diarrhoea)

30-39:

n/a

40-49:

Bone pain
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Migraine (headache)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Renal failure (kidney dysfunction)
Tearfulness (excess tearing)

50-59:

Chronic kidney disease

60+:

Chronic kidney disease
Vitreous haemorrhage (intraocular (inside the eye) bleeding)
Contusion (a type of hematoma of tissue in which capillaries)
Deafness unilateral
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dental discomfort
Dizziness
Drug ineffective
Dry mouth
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 23.81%
High Blood Cholesterol: 5 people, 23.81%
Pain: 4 people, 19.05%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 19.05%
Inflammation: 4 people, 19.05%
Constipation: 4 people, 19.05%
Neuralgia (pain in one or more nerves): 3 people, 14.29%
Nausea (feeling of having an urge to vomit): 3 people, 14.29%
Muscle Spasms (muscle contraction): 3 people, 14.29%
Muscle Aches (muscle pain): 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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