Temodar and Carboplatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Temodar (temozolomide) and Carboplatin (carboplatin). Common drug interactions include optic glioma among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Temodar and Carboplatin. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Temodar?

Temodar has active ingredients of temozolomide. It is often used in glioblastoma multiforme. eHealthMe is studying from 6,683 Temodar users. Check the latest studies of Temodar.

What is Carboplatin?

Carboplatin has active ingredients of carboplatin. It is often used in cancer. eHealthMe is studying from 128,210 Carboplatin users. Check the latest studies of Carboplatin.

On Aug, 04, 2026

95 people who take Temodar and Carboplatin together, and have interactions are studied.

Temodar and Carboplatin drug interactions.

What are the common drug interactions of Temodar and Carboplatin, by gender? *:

female:

Optic glioma (optic disc tumour)
Pain
Thrombocytopenia (decrease of platelets in blood)
Aphasia (damage to the parts of the brain that control language)
Hemiparesis (weakness on one side of the body)
Fatigue (feeling of tiredness)
Neoplasm progression (growth of tumour)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)

male:

Death
Disease progression
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Stomatitis (inflammation of mucous membrane of mouth)
Abdominal pain upper
Alanine aminotransferase increased
Anaemia (lack of blood)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug ineffective
Metastases to lung (cancer spreads to lung)

What are the common drug interactions of Temodar and Carboplatin, by age (0-1 to 60+)? *:

0-1:

Optic glioma (optic disc tumour)
Drug ineffective
Neoplasm progression (growth of tumour)

2-9:

Neuropathy peripheral (surface nerve damage)
Optic glioma (optic disc tumour)
Precocious puberty
Neoplasm progression (growth of tumour)
Anaphylactic reaction (serious allergic reaction)
Astrocytoma, low grade (low grade tumour of the brain that originate in a particular kind of glial-cells)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Distractibility (inability to sustain one's attention)
Drug ineffective
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)

10-19:

Optic glioma (optic disc tumour)
Abdominal pain upper
Oesophageal pain
Hypophagia (reduced food intake)
Stomatitis (inflammation of mucous membrane of mouth)
Anaemia (lack of blood)
Febrile neutropenia (fever with reduced white blood cells)
Mucosal inflammation (infection of mucous membrane)
Platelet count decreased

20-29:

n/a

30-39:

Adverse event
Blood pressure increased
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Neoplasm progression (growth of tumour)

40-49:

Somnolence (a state of near-sleep, a strong desire for sleep)
Upper-airway cough syndrome
Vomiting
White blood cell count decreased
Death
Headache (pain in head)
Fatigue (feeling of tiredness)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Disease progression

50-59:

Pain
Osteonecrosis (death of bone)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Constipation
Death
Decreased appetite
Diarrhoea
Fatigue (feeling of tiredness)
Hemiparesis (weakness on one side of the body)
Neutropenia (an abnormally low number of neutrophils)

60+:

Aphasia (damage to the parts of the brain that control language)
Cardiac failure congestive
Pain
Platelet count decreased
Rash
Respiratory failure (inadequate gas exchange by the respiratory system)
Thrombocytopenia (decrease of platelets in blood)
Death
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Brain Neoplasm Malignant (brain cancer tumour): 16 people, 16.84%
Optic Glioma (optic disc tumour): 11 people, 11.58%
Neuroblastoma (a cancer that forms in your nerve tissue): 7 people, 7.37%
Astrocytoma, Low Grade (low grade tumour of the brain that originate in a particular kind of glial-cells): 6 people, 6.32%
Lung Neoplasm Malignant (cancer tumour of lung): 5 people, 5.26%
Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 5 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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