Temovate and Elavil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Temovate (clobetasol propionate) and Elavil (amitriptyline hydrochloride). Common drug interactions include dehydration among females and acute respiratory distress syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Temovate and Elavil. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Temovate?

Temovate has active ingredients of clobetasol propionate. eHealthMe is studying from 1,392 Temovate users. Check the latest studies of Temovate.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.

On Jul, 08, 2026

18 people who take Temovate and Elavil together, and have interactions are studied.

What are the common drug interactions of Temovate and Elavil, by gender? *:

female:

Dehydration (dryness resulting from the removal of water)
Syncope (loss of consciousness with an inability to maintain postural tone)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Rash
Cataract (clouding of the lens inside the eye)
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Visual impairment
Agitation (state of anxiety or nervous excitement)
Angiopathy (generic term for a disease of the blood vessels)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

male:

Acute respiratory distress syndrome
Cellulitis (infection under the skin)
Staphylococcal infection (an infection with staphylococcus bacteria)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)
Sepsis (a severe blood infection that can lead to organ failure and death)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Device related infection
Injection site discharge
Injection site erythema (redness at injection site)

What are the common drug interactions of Temovate and Elavil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug hypersensitivity
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

Acute respiratory distress syndrome
Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Cellulitis (infection under the skin)
Acute respiratory distress syndrome
Asthenia (weakness)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Dehydration (dryness resulting from the removal of water)
Device related infection
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Injection site discharge
Injection site erythema (redness at injection site)

60+:

Hypercalcaemia (elevated calcium (ca+) level in the blood)
Alopecia (absence of hair from areas of the body)
Rash
Skin exfoliation (removal of the oldest dead skin cells)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug hypersensitivity
Erythema (redness of the skin)
Feeling hot
Iron deficiency anaemia

What are the existing conditions these people have? *

Pain: 8 people, 44.44%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 22.22%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 16.67%
Back Pain: 3 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 16.67%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 11.11%
Anaemia (lack of blood): 2 people, 11.11%
Diarrhea: 2 people, 11.11%
Headache (pain in head): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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