Temozolomide and Unituxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Temozolomide (temozolomide) and Unituxin (dinutuximab). Common drug interactions include bronchospasm among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Temozolomide and Unituxin. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Temozolomide?

Temozolomide has active ingredients of temozolomide. It is often used in glioblastoma multiforme. eHealthMe is studying from 16,644 Temozolomide users. Check the latest studies of Temozolomide.

What is Unituxin?

Unituxin has active ingredients of dinutuximab. eHealthMe is studying from 489 Unituxin users. Check the latest studies of Unituxin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 16, 2026

41 people who take Temozolomide and Unituxin together, and have interactions are studied.

Temozolomide and Unituxin drug interactions.

What are the common drug interactions of Temozolomide and Unituxin, by gender? *:

female:

  1. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  2. Hypersensitivity
  3. Abdominal distension
  4. Ascites (accumulation of fluid in the abdominal cavity)
  5. Cardiac arrest
  6. Cough
  7. Death
  8. Drug ineffective
  9. Dyspnoea (difficult or laboured respiration)
  10. Headache (pain in head)

male:

  1. Pyrexia (fever)
  2. C-reactive protein increased
  3. Neuroblastoma recurrent (reoccurrence of a cancer that forms in your nerve tissue)
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Hypokalaemia (low potassium)
  6. Nerve compression
  7. Oxygen saturation decreased
  8. Anaemia (lack of blood)
  9. Fatigue (feeling of tiredness)
  10. Leukocytosis (increased white blood cells)

What are the common drug interactions of Temozolomide and Unituxin, by age (0-1 to 60+)? *:

0-1:

  1. Anaphylactic reaction (serious allergic reaction)

2-9:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Antibody test positive
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  4. Anaphylactic reaction (serious allergic reaction)
  5. Pneumonia
  6. Pyrexia (fever)
  7. Hallucination (an experience involving the perception of something not present)
  8. Abdominal distension
  9. Ascites (accumulation of fluid in the abdominal cavity)
  10. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

10-19:

  1. Cardiac arrest
  2. Death
  3. Drug ineffective
  4. Dyspnoea (difficult or laboured respiration)
  5. Headache (pain in head)
  6. Hypotension (abnormally low blood pressure)
  7. Lethargy (tiredness)
  8. Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
  9. Metastatic neoplasm (spreadable cancer tumour)
  10. Neuroblastoma (a cancer that forms in your nerve tissue)

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain upper
  2. Asthenia (weakness)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Hypotension (abnormally low blood pressure)
  5. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  6. Nausea (feeling of having an urge to vomit)
  7. Neuralgia (pain in one or more nerves)
  8. Neuroblastoma (a cancer that forms in your nerve tissue)
  9. Pain in extremity
  10. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Neuroblastoma (a cancer that forms in your nerve tissue): 20 people, 48.78%
  2. Neuroblastoma Recurrent (reoccurrence of a cancer that forms in your nerve tissue): 11 people, 26.83%
  3. Pain: 5 people, 12.20%
  4. Metastases To Bone (cancer spreads to bone): 4 people, 9.76%
  5. Stress And Anxiety: 3 people, 7.32%
  6. Neoplasm Progression (growth of tumour): 3 people, 7.32%
  7. Metastases To Liver (cancer spreads to liver): 3 people, 7.32%
  8. Itching: 3 people, 7.32%
  9. Gastric Disorder (disease of stomach): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Temozolomide and Unituxin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Temozolomide and Unituxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Temozolomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Unituxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Temozolomide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Unituxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on temozolomide and dinutuximab (the active ingredients of Temozolomide and Unituxin, respectively), and Temozolomide and Unituxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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