Tessalon and Daliresp drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tessalon (benzonatate) and Daliresp (roflumilast). Common drug interactions include dyspnoea among females and haemoptysis among males.

The phase IV clinical study analyzes what interactions people have when they take Tessalon and Daliresp. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Tessalon?

Tessalon has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 6,493 Tessalon users. Check the latest studies of Tessalon.

What is Daliresp?

Daliresp has active ingredients of roflumilast. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 4,722 Daliresp users. Check the latest studies of Daliresp.

On Jul, 25, 2026

44 people who take Tessalon and Daliresp together, and have interactions are studied.

Tessalon and Daliresp drug interactions.

What are the common drug interactions of Tessalon and Daliresp, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Lung adenocarcinoma stage iii (the cancer has spread to nearby tissue or too far away lymph nodes)
Pneumonia
Wheezing (a high-pitched whistling sound made while you breath)
Asthenia (weakness)
Diarrhoea
Oral candidiasis (fungal infection of mouth)
Acute respiratory failure
Chest pain
Death

male:

Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Migraine (headache)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Blood pressure decreased
Burning sensation
Cardiac failure congestive
Chronic kidney disease
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)

What are the common drug interactions of Tessalon and Daliresp, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Back pain
Cold sweat
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Hot flush (sudden feelings of heat)
Hyperhidrosis (abnormally increased sweating)
Nervousness
Oral candidiasis (fungal infection of mouth)
Pruritus (severe itching of the skin)

50-59:

Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Chest pain
Fatigue (feeling of tiredness)
Wheezing (a high-pitched whistling sound made while you breath)
Abdominal pain
Anxiety disorder
Blood cholesterol increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac disorder
Chronic kidney disease

60+:

Pneumonia
Lung adenocarcinoma stage iii (the cancer has spread to nearby tissue or too far away lymph nodes)
Hypoxia (low oxygen in tissues)
Migraine (headache)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia bacterial (pneumonia associated with bacterial infection)
Respiratory tract congestion (blockage on respiratory system)
Weight fluctuation
Abdominal distension
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 13.64%
Multiple Myeloma (cancer of the plasma cells): 5 people, 11.36%
Asthma: 5 people, 11.36%
Obstructive Airways Disorder (a progressive disease that makes it hard to breathe): 4 people, 9.09%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 9.09%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 6.82%
Pain: 3 people, 6.82%
Diabetes: 3 people, 6.82%
Allergic Rhinitis: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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