Testosterone and Trintellix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Testosterone (testosterone) and Trintellix (vortioxetine hydrobromide). Common drug interactions include headache among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Testosterone and Trintellix. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Testosterone?

Testosterone has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 6,457 Testosterone users. Check the latest studies of Testosterone.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.



On Jul, 06, 2026

22 people who take Testosterone and Trintellix together, and have interactions are studied.

Testosterone and Trintellix drug interactions.

What are the common drug interactions of Testosterone and Trintellix, by gender? *:

female:

  1. Headache (pain in head)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Anxiety
  4. Back pain
  5. Bell's palsy (facial paralysis)
  6. Blood pressure decreased
  7. Blood sodium decreased
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Burning sensation
  10. Colitis (inflammation of colon)

male:

  1. Headache (pain in head)
  2. Suicidal ideation
  3. Joint injury
  4. Nausea (feeling of having an urge to vomit)
  5. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  6. Pulmonary function test decreased
  7. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  8. Abdominal pain upper
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Anxiety

What are the common drug interactions of Testosterone and Trintellix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anaemia (lack of blood)
  2. Hospitalisation
  3. Suicidal ideation
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Anxiety
  6. Bone density decreased
  7. Emotional distress
  8. Fracture
  9. Pain

40-49:

  1. Abdominal pain upper
  2. Diarrhoea
  3. Surgery

50-59:

  1. Head injury
  2. Anorgasmia (type of sexual dysfunction in which a person cannot achieve orgasm, even with adequate stimulation)
  3. Eating disorder
  4. Fall
  5. Headache (pain in head)
  6. Hypertension (high blood pressure)
  7. Injury
  8. Joint injury
  9. Loss of consciousness
  10. Pain

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 36.36%
  2. Drowsiness: 7 people, 31.82%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 27.27%
  4. Pain: 5 people, 22.73%
  5. High Blood Pressure: 4 people, 18.18%
  6. Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 3 people, 13.64%
  7. Sleep Disorder: 2 people, 9.09%
  8. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 9.09%
  9. Diarrhea: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Testosterone and Trintellix?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Testosterone and Trintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Testosterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Trintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Testosterone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trintellix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on testosterone and vortioxetine hydrobromide (the active ingredients of Testosterone and Trintellix, respectively), and Testosterone and Trintellix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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