Thalidomide and Gemfibrozil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Thalidomide (thalidomide) and Gemfibrozil (gemfibrozil). Common drug interactions include aspartate aminotransferase increased among females and bone disorder among males.
The phase IV clinical study analyzes what interactions people have when they take Thalidomide and Gemfibrozil. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.
What is Thalidomide?
Thalidomide has active ingredients of thalidomide. eHealthMe is studying from 16,473 Thalidomide users. Check the latest studies of Thalidomide.
What is Gemfibrozil?
Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.
48 people who take Thalidomide and Gemfibrozil together, and have interactions are studied.

What are the common drug interactions of Thalidomide and Gemfibrozil, by gender? *:
female:
- Aspartate aminotransferase increased
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
- Balance disorder
- Bone loss
- Chest discomfort
- Chest pain
- Coagulopathy (blood's ability to clot is impaired)
- Contusion (a type of hematoma of tissue in which capillaries)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
male:
- Bone disorder
- Arthralgia (joint pain)
- Gingival ulceration (ulcer on gums)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Loose tooth
- Multiple myeloma (cancer of the plasma cells)
- Oral pain
- Soft tissue inflammation
- Toothache (tooth pain)
- Wound dehiscence (a surgical incision reopens either internally or externally)
What are the common drug interactions of Thalidomide and Gemfibrozil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anxiety disorder
- Arthralgia (joint pain)
- Gait disturbance
- Joint stiffness
- Joint swelling
- Mobility decreased (ability to move is reduced)
- Muscle swelling
- Muscle tightness
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
50-59:
- Dyspnoea (difficult or laboured respiration)
- Flushing (the warm, red condition of human skin)
- Injury
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
- Microvascular angina (chest pain and angina in people who have no blockages in their coronary artery)
- Neck pain
- Oedema peripheral (superficial swelling)
- Open wound
- Osteomyelitis (infection of bone)
- Pain
60+:
- Bone disorder
- Depression
- Dyspnoea (difficult or laboured respiration)
- Gingival ulceration (ulcer on gums)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Loose tooth
- Multiple myeloma (cancer of the plasma cells)
- Oral pain
- Soft tissue inflammation
- Wound dehiscence (a surgical incision reopens either internally or externally)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 37 people, 77.08%
- Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 25 people, 52.08%
- Mood Swings (an extreme or rapid change in mood): 25 people, 52.08%
- Joint Pain: 25 people, 52.08%
- High Blood Pressure: 25 people, 52.08%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 25 people, 52.08%
- Diarrhea: 25 people, 52.08%
- Seasonal Allergy (allergic condition due to certain season): 18 people, 37.50%
- Blood Triglycerides Decreased: 18 people, 37.50%
* Approximation only. Some reports may have incomplete information.
Do you take Thalidomide and Gemfibrozil?
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- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Thalidomide (16,473 reports)
- Gemfibrozil (18,213 reports)
Browse all drug interactions of Thalidomide and Gemfibrozil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Thalidomide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Gemfibrozil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Thalidomide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gemfibrozil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on thalidomide and gemfibrozil (the active ingredients of Thalidomide and Gemfibrozil, respectively), and Thalidomide and Gemfibrozil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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