Theophylline and Bextra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Theophylline (theophylline) and Bextra (valdecoxib). Common drug interactions include poor dental condition among females and blood urine present among males.
The phase IV clinical study analyzes what interactions people have when they take Theophylline and Bextra. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.
What is Theophylline?
Theophylline has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 19,150 Theophylline users. Check the latest studies of Theophylline.
What is Bextra?
Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.
41 people who take Theophylline and Bextra together, and have interactions are studied.

What are the common drug interactions of Theophylline and Bextra, by gender? *:
female:
- Poor dental condition
- Postmenopause
- Weight decreased
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- General physical health deterioration (weak health status)
- Nausea (feeling of having an urge to vomit)
- Vomiting
- Bone disorder
- Osteonecrosis of jaw (death of bone of jaw)
- Malaise (a feeling of general discomfort or uneasiness)
male:
- Blood urine present
- Cough
- International normalised ratio decreased
What are the common drug interactions of Theophylline and Bextra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anaemia (lack of blood)
- Anxiety
- Decreased interest
- Injury
- Oedema peripheral (superficial swelling)
- Osteomyelitis (infection of bone)
- Poor dental condition
- Postmenopause
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- General physical health deterioration (weak health status)
50-59:
- Activities of daily living impaired
- Alopecia (absence of hair from areas of the body)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anal candidiasis (rectal fungal infection)
- Anaphylactic reaction (serious allergic reaction)
- Anxiety
- Arthralgia (joint pain)
- Back pain
- Blood cholesterol increased
- Blood glucose increased
60+:
- Oedema peripheral (superficial swelling)
- Arthralgia (joint pain)
- Erythema (redness of the skin)
- Fatigue (feeling of tiredness)
- Ganglion (a ganglion is a biological tissue mass, most commonly a mass of nerve cell bodies)
- Groin pain
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
- Nicotine dependence
- Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
- Pyrexia (fever)
What are the existing conditions these people have? *
- Breast Cancer: 13 people, 31.71%
- High Blood Pressure: 6 people, 14.63%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 14.63%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 9.76%
* Approximation only. Some reports may have incomplete information.
Do you take Theophylline and Bextra?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Theophylline (19,150 reports)
- Bextra (20,994 reports)
Browse all drug interactions of Theophylline and Bextra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Theophylline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Bextra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Theophylline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bextra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on theophylline and valdecoxib (the active ingredients of Theophylline and Bextra, respectively), and Theophylline and Bextra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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