Theophylline and Tarka drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Theophylline (theophylline) and Tarka (trandolapril; verapamil hydrochloride). Common drug interactions include pyrexia among females and abdominal neoplasm among males.

The phase IV clinical study analyzes what interactions people have when they take Theophylline and Tarka. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Theophylline?

Theophylline has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 19,150 Theophylline users. Check the latest studies of Theophylline.

What is Tarka?

Tarka has active ingredients of trandolapril; verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,409 Tarka users. Check the latest studies of Tarka.



On Jul, 15, 2026

11 people who take Theophylline and Tarka together, and have interactions are studied.

Theophylline and Tarka drug interactions.

What are the common drug interactions of Theophylline and Tarka, by gender? *:

female:

  1. Pyrexia (fever)
  2. Abnormal behaviour
  3. Arrhythmia (irregular heartbeat)
  4. Blood creatine phosphokinase mb increased
  5. Cardiac discomfort
  6. Cardiac failure
  7. Cholecystitis chronic (long lasting infection of gallbladder)
  8. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  9. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  10. Diabetes mellitus non-insulin-dependent

male:

  1. Abdominal neoplasm (cancer of the stomach)
  2. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  3. Myalgia (muscle pain)
  4. Suicide attempt
  5. Tremor (trembling or shaking movements in one or more parts of your body)
  6. Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
  7. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  8. Alopecia (absence of hair from areas of the body)
  9. Arthralgia (joint pain)
  10. Bradycardia (abnormally slow heart action)

What are the common drug interactions of Theophylline and Tarka, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Bradycardia (abnormally slow heart action)
  2. Hypotension (abnormally low blood pressure)
  3. Suicide attempt

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Alopecia (absence of hair from areas of the body)

60+:

  1. Abdominal neoplasm (cancer of the stomach)
  2. Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Arthralgia (joint pain)
  5. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Dyspnoea (difficult or laboured respiration)
  8. Face oedema (swelling of face)
  9. Muscle spasms (muscle contraction)
  10. Myalgia (muscle pain)

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 3 people, 27.27%
  2. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 27.27%
  3. Thyroid Diseases: 2 people, 18.18%
  4. Lung Disorder (lung disease): 2 people, 18.18%
  5. Inflammation: 2 people, 18.18%
  6. Hypersensitivity: 2 people, 18.18%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 18.18%
  8. Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 18.18%
  9. Cough: 2 people, 18.18%
  10. Cardiac Disorder: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Theophylline and Tarka:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Theophylline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tarka:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Theophylline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tarka and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on theophylline and trandolapril; verapamil hydrochloride (the active ingredients of Theophylline and Tarka, respectively), and Theophylline and Tarka (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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