Thiamine and Solu-cortef drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Thiamine (thiamine (vitamin b1)) and Solu-cortef (hydrocortisone sodium succinate). Common drug interactions include asthenia among females and abdominal pain among males.
The phase IV clinical study analyzes what interactions people have when they take Thiamine and Solu-cortef. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Thiamine?
Thiamine has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 11,036 Thiamine users. Check the latest studies of Thiamine.
What is Solu-cortef?
Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.
13 people who take Thiamine and Solu-cortef together, and have interactions are studied.

What are the common drug interactions of Thiamine and Solu-Cortef, by gender? *:
female:
- Asthenia (weakness)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Confusional state
- Dehydration (dryness resulting from the removal of water)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Nephropathy toxic (damage to kidney due to toxins)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Anaemia (lack of blood)
- Blood lactic acid increased
- Blood thyroid stimulating hormone decreased
male:
- Abdominal pain
- Cholangitis sclerosing (infection and obstruction of bile duct)
- Hypotension (abnormally low blood pressure)
- Memory impairment
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Victim of crime
- Constipation
What are the common drug interactions of Thiamine and Solu-Cortef, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Asthenia (weakness)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Confusional state
- Dehydration (dryness resulting from the removal of water)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Nephropathy toxic (damage to kidney due to toxins)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Anaemia (lack of blood)
- Blood lactic acid increased
- Blood thyroid stimulating hormone decreased
60+:
- Abdominal pain
- Abdominal discomfort
- Haematochezia (passage of stools containing blood)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Constipation
- Large intestine perforation (hole in large intestine)
- Asthenia (weakness)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Confusional state
- Sepsis (a severe blood infection that can lead to organ failure and death)
What are the existing conditions these people have? *
- Erdheim-Chester Disease (abnormal multiplication of a specific type of white blood cells): 5 people, 38.46%
- High Blood Cholesterol: 2 people, 15.38%
- Depression: 2 people, 15.38%
- Pain: 2 people, 15.38%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 15.38%
- Oedema (fluid collection in tissue): 2 people, 15.38%
- Back Pain: 2 people, 15.38%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 15.38%
- Sleep Disorder: 2 people, 15.38%
* Approximation only. Some reports may have incomplete information.
Do you take Thiamine and Solu-cortef?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Thiamine (11,036 reports)
- Solu-cortef (7,983 reports)
Browse all drug interactions of Thiamine and Solu-cortef:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Thiamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Solu-cortef:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Thiamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Solu-cortef and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on thiamine (vitamin b1) and hydrocortisone sodium succinate (the active ingredients of Thiamine and Solu-cortef, respectively), and Thiamine and Solu-cortef (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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