Thiotepa and Cancidas drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Thiotepa (thiotepa) and Cancidas (caspofungin acetate). Common drug interactions include blood culture positive among females and acute pulmonary oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Thiotepa and Cancidas. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Thiotepa?

Thiotepa has active ingredients of thiotepa. eHealthMe is studying from 8,097 Thiotepa users. Check the latest studies of Thiotepa.

What is Cancidas?

Cancidas has active ingredients of caspofungin acetate. eHealthMe is studying from 4,879 Cancidas users. Check the latest studies of Cancidas.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 04, 2026

12 people who take Thiotepa and Cancidas together, and have interactions are studied.

Thiotepa and Cancidas drug interactions.

What are the common drug interactions of Thiotepa and Cancidas, by gender? *:

female:

  1. Blood culture positive
  2. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  3. Device related infection
  4. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  5. Oesophagitis (inflammation of oesophagus)
  6. Pharyngeal inflammation
  7. Electrocardiogram qt prolonged
  8. Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
  9. Rash
  10. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

male:

  1. Acute pulmonary oedema (sudden deposit of fluid in the lung))
  2. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  5. Cystitis haemorrhagic (blood in the urine and painful voiding)
  6. Encephalopathy (functioning of the brain is affected by some agent or condition)
  7. Immunodeficiency
  8. Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
  9. Systemic candida (whole body fungal infection)
  10. Splenic candidiasis (fungal infection of spleen or near by)

What are the common drug interactions of Thiotepa and Cancidas, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood culture positive
  2. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  3. Device related infection
  4. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  5. Oesophagitis (inflammation of oesophagus)
  6. Pharyngeal inflammation
  7. Electrocardiogram qt prolonged
  8. Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)

50-59:

  1. Rash
  2. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

60+:

n/a

What are the existing conditions these people have? *

  1. Bone Marrow Conditioning Regimen: 9 people, 75.00%
  2. Urinary Tract Infection: 7 people, 58.33%
  3. Systemic Candida (whole body fungal infection): 7 people, 58.33%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 58.33%
  5. Hypotension (abnormally low blood pressure): 6 people, 50.00%
  6. Hypokinesia (decreased bodily movement): 6 people, 50.00%
  7. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 50.00%
  8. Venoocclusive Liver Disease (small veins in the liver are obstructed): 5 people, 41.67%
  9. Venoocclusive Disease (small veins in the liver are obstructed): 2 people, 16.67%
  10. Lung Disorder (lung disease): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Thiotepa and Cancidas:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Thiotepa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cancidas:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Thiotepa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cancidas and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on thiotepa and caspofungin acetate (the active ingredients of Thiotepa and Cancidas, respectively), and Thiotepa and Cancidas (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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