Thiotepa and Sofosbuvir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Thiotepa (thiotepa) and Sofosbuvir (sofosbuvir). Common drug interactions include cholestasis among females and cytomegalovirus infection among males.
The phase IV clinical study analyzes what interactions people have when they take Thiotepa and Sofosbuvir. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Thiotepa?
Thiotepa has active ingredients of thiotepa. eHealthMe is studying from 8,097 Thiotepa users. Check the latest studies of Thiotepa.
What is Sofosbuvir?
Sofosbuvir has active ingredients of sofosbuvir. eHealthMe is studying from 9,194 Sofosbuvir users. Check the latest studies of Sofosbuvir.
22 people who take Thiotepa and Sofosbuvir together, and have interactions are studied.
What are the common drug interactions of Thiotepa and Sofosbuvir, by gender? *:
female:
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Hepatic enzyme increased
- Hepatitis (inflammation of the liver)
male:
- Cytomegalovirus infection
- Soft tissue infection
- Hepatitis (inflammation of the liver)
What are the common drug interactions of Thiotepa and Sofosbuvir, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Viraemia (presence of a virus in the blood stream)
- Cytomegalovirus infection
- Soft tissue infection
- Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Hepatitis (inflammation of the liver)
- Hepatitis c virus test positive
- Hepatocellular injury (liver injury)
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Hepatic enzyme increased
60+:
- Hepatitis (inflammation of the liver)
What are the existing conditions these people have? *
- Hepatitis C: 14 people, 63.64%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 11 people, 50.00%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 5 people, 22.73%
- Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 13.64%
* Approximation only. Some reports may have incomplete information.
Do you take Thiotepa and Sofosbuvir?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Thiotepa (8,097 reports)
- Sofosbuvir (9,194 reports)
Browse all drug interactions of Thiotepa and Sofosbuvir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Thiotepa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sofosbuvir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Thiotepa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sofosbuvir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on thiotepa and sofosbuvir (the active ingredients of Thiotepa and Sofosbuvir, respectively), and Thiotepa and Sofosbuvir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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