Thorazine and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Thorazine (chlorpromazine hydrochloride) and Keppra (levetiracetam). Common drug interactions include neuropathy peripheral among females and balance disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Thorazine and Keppra. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Thorazine?

Thorazine has active ingredients of chlorpromazine hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 3,237 Thorazine users. Check the latest studies of Thorazine.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

On Jul, 20, 2026

25 people who take Thorazine and Keppra together, and have interactions are studied.

What are the common drug interactions of Thorazine and Keppra, by gender? *:

female:

Neuropathy peripheral (surface nerve damage)
Pancreatitis acute (sudden inflammation of pancreas)
Personality disorder
Pregnancy
Skin bacterial infection
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Suicidal ideation
Syncope (loss of consciousness with an inability to maintain postural tone)
Tardive dyskinesia (a disorder that involves involuntary movements)
Thyroid disorder (thyroid diseases)

male:

Balance disorder
Cerebral haemorrhage (bleeding within the brain)
Brain mass
Central nervous system lymphoma (cancer of central nervous system forms in lymph tissue)
Chest pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
Dry skin
Dyspepsia (indigestion)

What are the common drug interactions of Thorazine and Keppra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Ventricular extrasystoles (premature cardiac contraction)
Blood pressure decreased
Cardiac disorder
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Obesity (having too much body fat)
Petit mal epilepsy (absence seizure)
Suicide attempt
Type 2 diabetes mellitus

30-39:

Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nausea (feeling of having an urge to vomit)
Nerve injury
Neuropathy peripheral (surface nerve damage)
Oesophageal obstruction (blockage of oesophagus)
Pancreatitis acute (sudden inflammation of pancreas)
Personality disorder
Pregnancy
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Suicidal ideation

40-49:

Dyspnoea (difficult or laboured respiration)
Balance disorder
Cerebral haemorrhage (bleeding within the brain)
Constipation
Death
Fall
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Vision blurred
Weight decreased

50-59:

Drug hypersensitivity
Nausea (feeling of having an urge to vomit)
Type 2 diabetes mellitus
Peripheral swelling
Abdominal pain
Back disorder
Blood cholesterol increased
Diabetes mellitus inadequate control
Diarrhoea
Hyperlipidaemia (presence of excess lipids in the blood)

60+:

n/a

What are the existing conditions these people have? *

Migraine (headache): 4 people, 16.00%
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 4 people, 16.00%
Psychotic Disorder: 3 people, 12.00%
Pain: 3 people, 12.00%
Nausea (feeling of having an urge to vomit): 3 people, 12.00%
Insomnia (sleeplessness): 3 people, 12.00%
Depression: 3 people, 12.00%
Stress And Anxiety: 2 people, 8.00%
Sleep Disorder: 2 people, 8.00%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Thorazine and Keppra?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously