Thorazine and Restoril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Thorazine (chlorpromazine hydrochloride) and Restoril (temazepam). Common drug interactions include gastrooesophageal reflux disease among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Thorazine and Restoril. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Thorazine?

Thorazine has active ingredients of chlorpromazine hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 3,237 Thorazine users. Check the latest studies of Thorazine.

What is Restoril?

Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.

On Jul, 04, 2026

66 people who take Thorazine and Restoril together, and have interactions are studied.

Thorazine and Restoril drug interactions.

What are the common drug interactions of Thorazine and Restoril, by gender? *:

female:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Diabetes mellitus inadequate control
Dizziness
Tendonitis (a condition that causes pain and swelling of tendons)
Blood cholesterol increased
Conjunctival abrasion (injury to outer surface of eye)
Exostosis (formation of new bone on the surface of a bone)
Furuncle (infection of the hair follicle)
Melaena (the passage of black, tarry stools)
Neck pain

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperglycaemia (high blood sugar)
Depression
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Overdose
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Angiopathy (generic term for a disease of the blood vessels)
Brain damage

What are the common drug interactions of Thorazine and Restoril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Type 1 diabetes mellitus
Chest pain
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Drug ineffective
Somnolence (a state of near-sleep, a strong desire for sleep)
Type 2 diabetes mellitus
Back injury
Blood glucose increased
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)

30-39:

Type 2 diabetes mellitus
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Blood cholesterol increased
Depression
Pancreatitis (inflammation of pancreas)
Tardive dyskinesia (a disorder that involves involuntary movements)
Type 1 diabetes mellitus
Weight increased
Angiopathy (generic term for a disease of the blood vessels)
Diabetes mellitus inadequate control

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Type 2 diabetes mellitus
Hyperglycaemia (high blood sugar)
Brain damage
Cardiac disorder
Diabetes mellitus inadequate control
Neuropathy peripheral (surface nerve damage)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Diabetic complication
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)

50-59:

Renal failure chronic (long lasting kidney dysfunction)
Restlessness (not able to rest)
Schizoaffective disorder bipolar type (mental illness featuring schizophrenia and a mood disorder with mania)
Schizophrenia, paranoid type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect)
Suicidal ideation
Suicide attempt
Tachyphrenia (abnormally rapid mental activity)
Type 1 diabetes mellitus
Vision blurred
Weight decreased

60+:

Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Hemiplegia (paralysis of one side of the body)
Injury
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Migraine (headache)
Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Pain
Pancreatitis (inflammation of pancreas)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 18 people, 27.27%
Depression: 18 people, 27.27%
Sleep Disorder: 14 people, 21.21%
Stress And Anxiety: 12 people, 18.18%
Pain: 11 people, 16.67%
Agitation (state of anxiety or nervous excitement): 9 people, 13.64%
Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 10.61%
Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 9.09%
Affective Disorder (mental disorder): 5 people, 7.58%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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