Tigan and Actos drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tigan (trimethobenzamide hydrochloride) and Actos (pioglitazone hydrochloride). Common drug interactions include panic attack among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Tigan and Actos. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Tigan?

Tigan has active ingredients of trimethobenzamide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,904 Tigan users. Check the latest studies of Tigan.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,754 Actos users. Check the latest studies of Actos.

On Jul, 10, 2026

11 people who take Tigan and Actos together, and have interactions are studied.

What are the common drug interactions of Tigan and Actos, by gender? *:

female:

Panic attack
Parkinson's disease
Parkinsonian rest tremor
Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
Pruritus (severe itching of the skin)
Rectal haemorrhage (bleeding from anus)
Chest pain
Dizziness
Emotional disorder
Gait disturbance

male:

Drug ineffective
Dysgeusia (disorder of the sense of taste)
Somnolence (a state of near-sleep, a strong desire for sleep)
Stress
Adenocarcinoma pancreas (cancer of pancreas)
Anxiety
Blood pressure decreased
Fall
Granulocytopenia (lack of granulocyte)
Leukopenia (less number of white blood cells in blood)

What are the common drug interactions of Tigan and Actos, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Fibromyalgia (a long-term condition which causes pain all over the body)
Hysterectomy
Intervertebral disc protrusion (spinal disc protrusion)

40-49:

n/a

50-59:

n/a

60+:

Drug ineffective
Adenocarcinoma pancreas (cancer of pancreas)
Anxiety
Blood pressure decreased
Dysgeusia (disorder of the sense of taste)
Fall
Granulocytopenia (lack of granulocyte)
Leukopenia (less number of white blood cells in blood)
Somnolence (a state of near-sleep, a strong desire for sleep)
Stress

What are the existing conditions these people have? *

Quit Smoking: 4 people, 36.36%
Parkinson's Disease: 3 people, 27.27%
Back Pain: 3 people, 27.27%
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 1 person, 9.09%
Nausea And Vomiting: 1 person, 9.09%
Impaired Gastric Emptying: 1 person, 9.09%
Hyperinsulinaemia (excess levels of insulin circulating in the blood): 1 person, 9.09%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 9.09%
Delusion (a false belief or opinion): 1 person, 9.09%
Back Injury: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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