Tigan and Atrovent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tigan (trimethobenzamide hydrochloride) and Atrovent (ipratropium bromide). Common drug interactions include drug hypersensitivity among females and disorientation among males.

The phase IV clinical study analyzes what interactions people have when they take Tigan and Atrovent. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Tigan?

Tigan has active ingredients of trimethobenzamide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,904 Tigan users. Check the latest studies of Tigan.

What is Atrovent?

Atrovent has active ingredients of ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 33,210 Atrovent users. Check the latest studies of Atrovent.



On Jul, 18, 2026

17 people who take Tigan and Atrovent together, and have interactions are studied.

Tigan and Atrovent drug interactions.

What are the common drug interactions of Tigan and Atrovent, by gender? *:

female:

  1. Drug hypersensitivity
  2. Anorectal discomfort
  3. Atelectasis (partial or complete collapse of the lung)
  4. Chills (felling of cold)
  5. Chronic kidney disease
  6. Dyskinesia (abnormality or impairment of voluntary movement)
  7. Dyspnoea (difficult or laboured respiration)
  8. Failure to thrive (inadequate weight gain and physical growth in children)
  9. Fatigue (feeling of tiredness)
  10. Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)

male:

  1. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  2. Pancreatitis (inflammation of pancreas)
  3. Fatigue (feeling of tiredness)
  4. Flatulence (flatus expelled through the anus)
  5. Gait disturbance
  6. Hypertension (high blood pressure)
  7. Hypokalaemia (low potassium)
  8. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  9. Hypotension (abnormally low blood pressure)
  10. Oedema peripheral (superficial swelling)

What are the common drug interactions of Tigan and Atrovent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  2. Pancreatitis (inflammation of pancreas)
  3. Drug hypersensitivity
  4. Atelectasis (partial or complete collapse of the lung)
  5. Overdose
  6. Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)
  7. Pseudarthrosis (bones that do not heal after fracture)
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Spinal osteoarthritis (joint cartilage loss in spine)

50-59:

  1. Failure to thrive (inadequate weight gain and physical growth in children)
  2. Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
  3. Liver injury

60+:

  1. Fatigue (feeling of tiredness)
  2. Arthralgia (joint pain)
  3. Gait disturbance
  4. Hypertension (high blood pressure)
  5. Hypokalaemia (low potassium)
  6. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  7. Hypotension (abnormally low blood pressure)
  8. Oedema peripheral (superficial swelling)
  9. Pain
  10. Pain in extremity

What are the existing conditions these people have? *

  1. Pain: 4 people, 23.53%
  2. Type 2 Diabetes: 3 people, 17.65%
  3. Stress And Anxiety: 3 people, 17.65%
  4. Asthma: 3 people, 17.65%
  5. Parkinson's Disease: 3 people, 17.65%
  6. Back Pain: 3 people, 17.65%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
  8. High Blood Cholesterol: 3 people, 17.65%
  9. Breakthrough Pain: 2 people, 11.76%
  10. Constipation: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Tigan and Atrovent?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tigan and Atrovent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tigan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Atrovent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tigan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atrovent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on trimethobenzamide hydrochloride and ipratropium bromide (the active ingredients of Tigan and Atrovent, respectively), and Tigan and Atrovent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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