Tigan and Fentanyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tigan (trimethobenzamide hydrochloride) and Fentanyl (fentanyl citrate). Common drug interactions include fungal infection among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Tigan and Fentanyl. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Tigan?

Tigan has active ingredients of trimethobenzamide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,904 Tigan users. Check the latest studies of Tigan.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

On Jul, 24, 2026

53 people who take Tigan and Fentanyl together, and have interactions are studied.

What are the common drug interactions of Tigan and Fentanyl, by gender? *:

female:

Fungal infection
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Lung disorder (lung disease)
Malaise (a feeling of general discomfort or uneasiness)
Osteoporosis (bones weak and more likely to break)
Fatigue (feeling of tiredness)
Agitation (state of anxiety or nervous excitement)
Body height decreased
Cardiac disorder
Drug ineffective

male:

Cardiac failure congestive
Arrhythmia (irregular heartbeat)
Hepatic failure (liver failure)
Liver disorder (liver diseases)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Renal failure acute (rapid kidney dysfunction)
Septic shock (shock due to blood infection)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Pneumonia

What are the common drug interactions of Tigan and Fentanyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dizziness
Euphoric mood (excessively happy but may become angry or irritable)
Overdose
Vomiting
Activities of daily living impaired
Drug toxicity
Abdominal pain
Abdominal pain upper
Asthenia (weakness)
Blood potassium decreased

40-49:

Fall
Fatigue (feeling of tiredness)
Headache (pain in head)
Lower limb fracture
Somnambulism (sleep walking)
Accidental exposure
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Confusional state
Dysarthria (speech disorder)
Eye rolling

50-59:

Hepatic failure (liver failure)
Liver disorder (liver diseases)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Renal failure acute (rapid kidney dysfunction)
Septic shock (shock due to blood infection)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pneumonia
Serratia bacteraemia (bacterial blood infection)
Staphylococcal bacteraemia (a bacterial infection of blood)

60+:

Asthenia (weakness)
Anaemia (lack of blood)
Blood urea decreased
Bone disorder
Bone fragmentation
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Cachexia (loss of weight)
Cardiac failure congestive
Deformity (disfigurement)
Dental caries

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 15.09%
Diabetes: 8 people, 15.09%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 6 people, 11.32%
Blood Pressure Abnormal: 6 people, 11.32%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 6 people, 11.32%
Feeling Of Relaxation: 6 people, 11.32%
Glaucoma (increased fluid pressure in the eye with vision loss): 6 people, 11.32%
Glossitis (infection of tongue with soreness): 6 people, 11.32%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 6 people, 11.32%
High Blood Cholesterol: 6 people, 11.32%

* Approximation only. Some reports may have incomplete information.

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