Tikosyn and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tikosyn (dofetilide) and Colace (docusate ). Common drug interactions include body height decreased among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Tikosyn and Colace. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Tikosyn?

Tikosyn has active ingredients of dofetilide. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 12,202 Tikosyn users. Check the latest studies of Tikosyn.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

On Aug, 12, 2026

69 people who take Tikosyn and Colace together, and have interactions are studied.

What are the common drug interactions of Tikosyn and Colace, by gender? *:

female:

Body height decreased
Gastric haemorrhage (bleeding stomach)
Haemoglobin decreased
Hypoacusis (loss of hearing)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Weight increased
Anaemia (lack of blood)
Blood glucose decreased
Cardiac failure
Cardiac failure congestive

male:

Weight decreased
Cardiac failure congestive
Pleural effusion (water on the lungs)
Prostate cancer
Cardiac arrest
Pneumonia
Blood urea increased
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Fall
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Tikosyn and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Headache (pain in head)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Pyrexia (fever)

50-59:

Dizziness (excl vertigo)
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Eating disorder
Euphoric mood (excessively happy but may become angry or irritable)
Increased activity
Loss of control of legs
Nervousness
Palpitations (feelings or sensations that your heart is pounding or racing)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

60+:

Electrocardiogram qt prolonged
Cardiac failure congestive
Hemiparesis (weakness on one side of the body)
Micturition urgency (urgency to pass the urine)
Paralysis
Renal cancer (cancer of kidney)
Vertigo
Blood calcium decreased
Cardiomyopathy (weakening of the heart muscle)
Fall

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 10.14%
High Blood Cholesterol: 7 people, 10.14%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 7.25%
Stress And Anxiety: 4 people, 5.80%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 5.80%
Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 5.80%
Chest Pain: 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

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