Tikosyn and Methylprednisolone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tikosyn (dofetilide) and Methylprednisolone (methylprednisolone). Common drug interactions include heart rate increased among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Tikosyn and Methylprednisolone. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Tikosyn?

Tikosyn has active ingredients of dofetilide. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 12,202 Tikosyn users. Check the latest studies of Tikosyn.

What is Methylprednisolone?

Methylprednisolone has active ingredients of methylprednisolone. It is often used in inflammation. eHealthMe is studying from 59,645 Methylprednisolone users. Check the latest studies of Methylprednisolone.

On Aug, 08, 2026

23 people who take Tikosyn and Methylprednisolone together, and have interactions are studied.

Tikosyn and Methylprednisolone drug interactions.

What are the common drug interactions of Tikosyn and Methylprednisolone, by gender? *:

female:

Heart rate increased
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Abdominal pain upper
Anaemia (lack of blood)
Blood potassium increased
Dizziness
Hot flush (sudden feelings of heat)
Injury
Malaise (a feeling of general discomfort or uneasiness)
Pain in jaw

male:

Cardiac failure congestive
Back pain
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Multiple injuries
Syncope (loss of consciousness with an inability to maintain postural tone)
Abdominal pain
Cardiomyopathy (weakening of the heart muscle)
Partner stress
Renal cell carcinoma (a kidney cancer)

What are the common drug interactions of Tikosyn and Methylprednisolone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood pressure increased
Headache (pain in head)
Pain
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Anxiety
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Blood glucose increased
Blood pressure decreased

50-59:

Hallucination, visual (seeing things that aren't there)
Headache (pain in head)
Herpes zoster
Hot flush (sudden feelings of heat)
Hyperhidrosis (abnormally increased sweating)
Swelling
Abnormal behaviour
Agitation (state of anxiety or nervous excitement)
Asthma
Atrial tachycardia (rhythm disturbance that arises in the atria)

60+:

Pain
Cardiac failure congestive
Multiple injuries
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Emotional disorder
Fatigue (feeling of tiredness)
Syncope (loss of consciousness with an inability to maintain postural tone)
Abdominal pain
Cardiomyopathy (weakening of the heart muscle)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Atrial Tachycardia (rhythm disturbance that arises in the atria): 7 people, 30.43%
Cardiac Failure Congestive: 4 people, 17.39%
Cardiac Disorder: 4 people, 17.39%
Nausea (feeling of having an urge to vomit): 2 people, 8.70%
Multiple Myeloma (cancer of the plasma cells): 2 people, 8.70%
Indigestion: 2 people, 8.70%
Ill-Defined Disorder: 2 people, 8.70%
Hypersensitivity: 2 people, 8.70%
Arrhythmias (irregular heartbeat): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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