Tikosyn and Remodulin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tikosyn (dofetilide) and Remodulin (treprostinil sodium). Common drug interactions include nausea among females and infusion site discolouration among males.

The phase IV clinical study analyzes what interactions people have when they take Tikosyn and Remodulin. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Tikosyn?

Tikosyn has active ingredients of dofetilide. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 12,202 Tikosyn users. Check the latest studies of Tikosyn.

What is Remodulin?

Remodulin has active ingredients of treprostinil sodium. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,843 Remodulin users. Check the latest studies of Remodulin.

On Jul, 06, 2026

22 people who take Tikosyn and Remodulin together, and have interactions are studied.

Tikosyn and Remodulin drug interactions.

What are the common drug interactions of Tikosyn and Remodulin, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Vomiting
Renal failure (kidney dysfunction)
Death
Flushing (the warm, red condition of human skin)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Insomnia (sleeplessness)
Menstrual disorder (disease of menstrual cycle)
Pain in extremity
Restlessness (not able to rest)

male:

Infusion site discolouration
Infusion site pain
Infusion site vesicles (fluid- or air-filled cavity or sac at infusion site)
Seasonal allergy (allergic condition due to certain season)
Therapeutic response decreased (less preventive response)

What are the common drug interactions of Tikosyn and Remodulin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Headache (pain in head)
Pain in jaw
Cardiac failure
Diarrhoea
Death
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Insomnia (sleeplessness)
Menstrual disorder (disease of menstrual cycle)
Nausea (feeling of having an urge to vomit)
Pain in extremity

50-59:

Hypotension (abnormally low blood pressure)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Blood creatinine decreased
Blood pressure decreased
Cystitis (inflammation of the wall of the bladder)
Dyspnoea (difficult or laboured respiration)
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Interstitial lung disease
Renal failure (kidney dysfunction)
Septic shock (shock due to blood infection)

60+:

Catheter site cellulitis (infection of cells near catheter)
Infection
Infusion site discolouration
Infusion site pain
Infusion site vesicles (fluid- or air-filled cavity or sac at infusion site)
Seasonal allergy (allergic condition due to certain season)
Therapeutic response decreased (less preventive response)

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 9 people, 40.91%
Pain: 4 people, 18.18%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 9.09%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 9.09%
Dry Eyes (lack of adequate tears): 2 people, 9.09%
Diarrhea: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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