Timoptic and Vasotec drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Timoptic (timolol maleate) and Vasotec (enalapril maleate). Common drug interactions include antinuclear factor positive among females and diabetes mellitus among males.
The phase IV clinical study analyzes what interactions people have when they take Timoptic and Vasotec. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.
What is Timoptic?
Timoptic has active ingredients of timolol maleate. It is often used in glaucoma. eHealthMe is studying from 4,247 Timoptic users. Check the latest studies of Timoptic.
What is Vasotec?
Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.
61 people who take Timoptic and Vasotec together, and have interactions are studied.

What are the common drug interactions of Timoptic and Vasotec, by gender? *:
female:
- Antinuclear factor positive
- Cardiac failure congestive
- Fracture displacement
- Ilium fracture
- Pulmonary mass
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Autoimmune hepatitis
- Blood albumin decreased
- Blood bilirubin increased
male:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Cardiac disorder
- Impaired healing
- Neuropathy peripheral (surface nerve damage)
- Retroperitoneal haemorrhage (bleeding between the peritoneum and the posterior abdominal wall)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Abscess (pus)
- Alanine aminotransferase increased
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Arrhythmia (irregular heartbeat)
What are the common drug interactions of Timoptic and Vasotec, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Cardiac disorder
- Circulatory collapse
- Death
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Sick sinus syndrome (a collection of heart rhythm disorders)
- Type 2 diabetes mellitus
- Arthropathy
- Neuropathy peripheral (surface nerve damage)
- Arrhythmia (irregular heartbeat)
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
50-59:
- Smooth muscle antibody positive
- Antinuclear factor positive
- Autoimmune hepatitis
- Blood albumin decreased
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Blood bilirubin increased
60+:
- Weight decreased
- Dyspnoea (difficult or laboured respiration)
- Anaemia (lack of blood)
- Balance disorder
- Death
- Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
- Dry skin
- Fall
- Haematochezia (passage of stools containing blood)
- Haemorrhage (bleeding)
What are the existing conditions these people have? *
- Osteoporosis (bones weak and more likely to break): 7 people, 11.48%
- Stress And Anxiety: 6 people, 9.84%
- Nervousness: 6 people, 9.84%
- Insomnia (sleeplessness): 6 people, 9.84%
- Facial Nerve Disorder (disease of face nerve): 6 people, 9.84%
- Depression: 6 people, 9.84%
* Approximation only. Some reports may have incomplete information.
Do you take Timoptic and Vasotec?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Timoptic and Vasotec:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Timoptic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vasotec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Timoptic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vasotec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on timolol maleate and enalapril maleate (the active ingredients of Timoptic and Vasotec, respectively), and Timoptic and Vasotec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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