Tirosint and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tirosint (levothyroxine sodium) and Digoxin (digoxin). Common drug interactions include convulsion among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Tirosint and Digoxin. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Tirosint?

Tirosint has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 5,001 Tirosint users. Check the latest studies of Tirosint.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

17 people who take Tirosint and Digoxin together, and have interactions are studied.

What are the common drug interactions of Tirosint and Digoxin, by gender? *:

female:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Cerebral haematoma (collection of blood in brain)
Dyspnoea (difficult or laboured respiration)
Ear pain
Fluid overload (too much fluid in the blood)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Mitral valve incompetence (inefficient heart valve)
Neck pain

male:

Asthenia (weakness)
Bradycardia (abnormally slow heart action)
Cardiogenic shock (inadequate circulation of blood)
Hyperkalaemia (damage to or disease of the kidney)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Tirosint and Digoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

50-59:

Respiratory tract infection fungal

60+:

Cardiac failure congestive
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Hyperkalaemia (damage to or disease of the kidney)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Mitral valve incompetence (inefficient heart valve)
Neck pain
Oedema (fluid collection in tissue)
Oropharyngeal pain

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 17.65%
High Blood Pressure: 3 people, 17.65%
Urination - Excessive Volume: 1 person, 5.88%
Heart Rate Irregular: 1 person, 5.88%
Bone Disorder: 1 person, 5.88%
Cardiac Disorder: 1 person, 5.88%
Cardiac Failure: 1 person, 5.88%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 5.88%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 1 person, 5.88%
Ear Disorder: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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