Tirosint and Fluconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tirosint (levothyroxine sodium) and Fluconazole (fluconazole). Common drug interactions include sinusitis among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Tirosint and Fluconazole. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Tirosint?

Tirosint has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 5,000 Tirosint users. Check the latest studies of Tirosint.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

On Jul, 13, 2026

56 people who take Tirosint and Fluconazole together, and have interactions are studied.

Tirosint and Fluconazole drug interactions.

What are the common drug interactions of Tirosint and Fluconazole, by gender? *:

female:

Sinusitis (inflammation of sinus)
Headache (pain in head)
Impaired gastric emptying
Fungal infection
Infusion site pain
Nausea (feeling of having an urge to vomit)
Anaemia (lack of blood)
Chest discomfort
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dehydration (dryness resulting from the removal of water)

male:

Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Renal impairment (severely reduced kidney function)
Anxiety
Bone density decreased
Chronic kidney disease
Emotional distress
Hypertension (high blood pressure)
Osteoporosis (bones weak and more likely to break)
Pain

What are the common drug interactions of Tirosint and Fluconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Dehydration (dryness resulting from the removal of water)
Depression
Diarrhoea
Dysarthria (speech disorder)
Fluid retention (an abnormal accumulation of fluid in the blood)
Nausea (feeling of having an urge to vomit)
Neurological symptom (symptoms of nervous system disease)
Pain
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

Surgery
Depression
Colitis ulcerative (inflammation of colon with ulcer)

40-49:

Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Hepatocellular injury (liver injury)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Chronic kidney disease
Emotional distress
Hypertension (high blood pressure)
Osteoporosis (bones weak and more likely to break)

50-59:

Rash
Anaphylactic reaction (serious allergic reaction)
Anxiety disorder
Drug ineffective
Fungal infection
Infection
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Nephrolithiasis (calculi in the kidneys)
Oral herpes (viral infection of mouth)
Pruritus (severe itching of the skin)

60+:

Sinusitis (inflammation of sinus)
Body temperature decreased
Acute sinusitis
Back pain
Chronic kidney disease
Drug ineffective
Fatigue (feeling of tiredness)
Haematuria (presence of blood in urine)
Headache (pain in head)
Hypertension (high blood pressure)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 32.14%
Immunodeficiency Common Variable: 13 people, 23.21%
Sleep Disorder: 6 people, 10.71%
Fungal Nail Infection: 4 people, 7.14%
Migraine (headache): 3 people, 5.36%
Drowsiness: 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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