Tivicay and Copegus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tivicay (dolutegravir sodium) and Copegus (ribavirin). Common drug interactions include pulmonary arterial hypertension among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Tivicay and Copegus. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Tivicay?

Tivicay has active ingredients of dolutegravir sodium. It is often used in hiv infection. eHealthMe is studying from 9,674 Tivicay users. Check the latest studies of Tivicay.

What is Copegus?

Copegus has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 15,115 Copegus users. Check the latest studies of Copegus.



On Jul, 07, 2026

16 people who take Tivicay and Copegus together, and have interactions are studied.

Tivicay and Copegus drug interactions.

What are the common drug interactions of Tivicay and Copegus, by gender? *:

female:

  1. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
  2. Abdominal pain upper
  3. Anaemia (lack of blood)
  4. Flatulence (flatus expelled through the anus)
  5. Headache (pain in head)

male:

  1. Anaemia (lack of blood)
  2. Bile duct stone
  3. Ataxia (loss of full control of bodily movements)
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Confusional state
  6. Dysarthria (speech disorder)
  7. Gastritis (inflammation of stomach)
  8. Hyperammonaemia
  9. Hyperammonaemic encephalopathy (excess of ammonia in the blood, disorder or disease of the brain)
  10. Impatience (restlessness)

What are the common drug interactions of Tivicay and Copegus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Bile duct stone
  2. Aggression
  3. Anaemia (lack of blood)
  4. Fatigue (feeling of tiredness)
  5. Headache (pain in head)
  6. Syncope (loss of consciousness with an inability to maintain postural tone)
  7. Confusional state
  8. Impatience (restlessness)
  9. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  10. Sleep disorder

40-49:

  1. Drug ineffective
  2. Transaminases increased
  3. Anaemia (lack of blood)
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Gastritis (inflammation of stomach)
  6. Loss of consciousness
  7. Renal failure (kidney dysfunction)
  8. Syncope (loss of consciousness with an inability to maintain postural tone)
  9. Tibia fracture (fracture of lower leg bone)

50-59:

  1. Hepatic failure (liver failure)
  2. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
  3. Hyperammonaemic encephalopathy (excess of ammonia in the blood, disorder or disease of the brain)
  4. Rash
  5. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  6. Abdominal pain upper
  7. Anaemia (lack of blood)
  8. Flatulence (flatus expelled through the anus)
  9. Headache (pain in head)
  10. Ataxia (loss of full control of bodily movements)

60+:

n/a

What are the existing conditions these people have? *

  1. Rickets (softening of bones): 2 people, 12.50%
  2. Pancreatic Insufficiency: 2 people, 12.50%
  3. Diabetes: 2 people, 12.50%
  4. Depression: 2 people, 12.50%
  5. Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 2 people, 12.50%
  6. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 6.25%
  7. High Blood Pressure: 1 person, 6.25%
  8. Gastritis (inflammation of stomach): 1 person, 6.25%
  9. Acute Hiv Infection: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tivicay and Copegus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tivicay:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Copegus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tivicay and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Copegus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dolutegravir sodium and ribavirin (the active ingredients of Tivicay and Copegus, respectively), and Tivicay and Copegus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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