Tizanidine hydrochloride and Benlysta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tizanidine hydrochloride (tizanidine hydrochloride) and Benlysta (belimumab). Common drug interactions include oedema peripheral among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Tizanidine hydrochloride and Benlysta. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Tizanidine hydrochloride?

Tizanidine hydrochloride has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 7,453 Tizanidine hydrochloride users. Check the latest studies of Tizanidine hydrochloride.

What is Benlysta?

Benlysta has active ingredients of belimumab. It is often used in systemic lupus erythematosus. eHealthMe is studying from 23,528 Benlysta users. Check the latest studies of Benlysta.



On Jul, 09, 2026

27 people who take Tizanidine hydrochloride and Benlysta together, and have interactions are studied.

Tizanidine hydrochloride and Benlysta drug interactions.

What are the common drug interactions of Tizanidine Hydrochloride and Benlysta, by gender? *:

female:

  1. Oedema peripheral (superficial swelling)
  2. Sinusitis (inflammation of sinus)
  3. Diarrhoea
  4. Nausea (feeling of having an urge to vomit)
  5. Urinary tract infection
  6. Chest discomfort
  7. Dyspnoea (difficult or laboured respiration)
  8. Fatigue (feeling of tiredness)
  9. Headache (pain in head)
  10. Poor venous access

male:

  1. Diarrhoea
  2. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  3. Oedema peripheral (superficial swelling)
  4. Pruritus (severe itching of the skin)
  5. Rash vesicular (rash with a small bubble)
  6. Red blood cell count decreased
  7. Urinary tract infection
  8. White blood cell count decreased
  9. Butterfly rash
  10. Cough

What are the common drug interactions of Tizanidine Hydrochloride and Benlysta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Fatigue (feeling of tiredness)
  2. Headache (pain in head)
  3. Infusion related reaction
  4. Insomnia (sleeplessness)
  5. Joint swelling
  6. Nausea (feeling of having an urge to vomit)
  7. Peripheral swelling
  8. Phlebitis (inflammation of the walls of a vein)
  9. Sinusitis (inflammation of sinus)
  10. Urinary tract infection

40-49:

  1. Sinusitis (inflammation of sinus)
  2. Poor venous access
  3. Arthralgia (joint pain)
  4. Chills (felling of cold)
  5. Drug ineffective
  6. Migraine (headache)
  7. Oedema peripheral (superficial swelling)
  8. Respiratory syncytial virus infection (viral disease of respiratory system)
  9. Throat irritation
  10. Upper respiratory tract infection

50-59:

  1. Abdominal pain
  2. Abdominal tenderness
  3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  4. Chest discomfort
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  6. Diarrhoea
  7. Dysgeusia (disorder of the sense of taste)
  8. Dysphonia (speech disorder attributable to a disorder of phonation)
  9. Dyspnoea (difficult or laboured respiration)
  10. Fatigue (feeling of tiredness)

60+:

  1. Diarrhoea
  2. Oedema peripheral (superficial swelling)
  3. Death
  4. Erythema (redness of the skin)
  5. Exposed bone in jaw
  6. Fall
  7. Full blood count decreased
  8. Gingival infection (gum infection)
  9. Local swelling (swelling at the site of some application of substance or injury)
  10. Lung neoplasm malignant (cancer tumour of lung)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 7 people, 25.93%
  2. Pain: 2 people, 7.41%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.41%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Tizanidine hydrochloride and Benlysta?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tizanidine hydrochloride and Benlysta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tizanidine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Benlysta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tizanidine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Benlysta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tizanidine hydrochloride and belimumab (the active ingredients of Tizanidine hydrochloride and Benlysta, respectively), and Tizanidine hydrochloride and Benlysta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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