Tizanidine hydrochloride and Thiamine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tizanidine hydrochloride (tizanidine hydrochloride) and Thiamine hydrochloride (thiamine hydrochloride). Common drug interactions include gastrooesophageal reflux disease among females and colitis among males.

The phase IV clinical study analyzes what interactions people have when they take Tizanidine hydrochloride and Thiamine hydrochloride. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Tizanidine hydrochloride?

Tizanidine hydrochloride has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 7,453 Tizanidine hydrochloride users. Check the latest studies of Tizanidine hydrochloride.

What is Thiamine hydrochloride?

Thiamine hydrochloride has active ingredients of thiamine hydrochloride. eHealthMe is studying from 2,046 Thiamine hydrochloride users. Check the latest studies of Thiamine hydrochloride.



On Jul, 20, 2026

62 people who take Tizanidine hydrochloride and Thiamine hydrochloride together, and have interactions are studied.

Tizanidine hydrochloride and Thiamine hydrochloride drug interactions.

What are the common drug interactions of Tizanidine Hydrochloride and Thiamine Hydrochloride, by gender? *:

female:

  1. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  2. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  5. Infusion site mass
  6. Infusion site pruritus (severe itching at infusion site)
  7. Injection site pain
  8. Oral discomfort (pain or irritation in mouth)
  9. Oropharyngeal discomfort (pain or irritation of oropharynx)
  10. Seasonal allergy (allergic condition due to certain season)

male:

  1. Colitis (inflammation of colon)
  2. Eye pain
  3. Fatigue (feeling of tiredness)
  4. Foreign body sensation in eyes (feeling of something in eye)
  5. Gastritis (inflammation of stomach)
  6. Ocular hyperaemia (an abnormally large amount of blood in eye)
  7. Photophobia (extreme sensitivity to light)
  8. Skin fissures (a crack in the skin)
  9. Vision blurred

What are the common drug interactions of Tizanidine Hydrochloride and Thiamine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Fatigue (feeling of tiredness)
  2. Chest pain
  3. Device dislocation
  4. Dyspnoea (difficult or laboured respiration)
  5. Epistaxis (bleed from the nose)
  6. Eye pain
  7. Foreign body sensation in eyes (feeling of something in eye)
  8. Hypotension (abnormally low blood pressure)
  9. Injection site reaction
  10. Ocular hyperaemia (an abnormally large amount of blood in eye)

60+:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Seasonal allergy (allergic condition due to certain season)
  4. Weight increased
  5. Infusion site discomfort
  6. Infusion site haemorrhage (bleeding from infusion site)
  7. Infusion site irritation
  8. Infusion site pain
  9. Urinary tract infection
  10. Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

  1. Pain: 43 people, 69.35%
  2. Immunodeficiency Common Variable: 6 people, 9.68%
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Tizanidine hydrochloride and Thiamine hydrochloride?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tizanidine hydrochloride and Thiamine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tizanidine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Thiamine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tizanidine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Thiamine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tizanidine hydrochloride and thiamine hydrochloride (the active ingredients of Tizanidine hydrochloride and Thiamine hydrochloride, respectively), and Tizanidine hydrochloride and Thiamine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: