Tobradex and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tobradex (dexamethasone; tobramycin) and Acyclovir (acyclovir). Common drug interactions include skin hyperpigmentation among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Tobradex and Acyclovir. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Tobradex?

Tobradex has active ingredients of dexamethasone; tobramycin. It is often used in eye infection. eHealthMe is studying from 3,154 Tobradex users. Check the latest studies of Tobradex.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

On Jul, 18, 2026

66 people who take Tobradex and Acyclovir together, and have interactions are studied.

Tobradex and Acyclovir drug interactions.

What are the common drug interactions of Tobradex and Acyclovir, by gender? *:

female:

Skin hyperpigmentation (disorders affect the colour of your skin)
Skin hypertrophy (skin cells enlarges)
Skin induration (an abnormally hard spot or area on the skin)
Skin tightness
Chest pain
Headache (pain in head)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)

male:

Anaemia (lack of blood)
Anxiety
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Bone disorder
Fistula (an abnormal connection or passageway between two)
Gingivitis (inflammation of gums)
Hepatomegaly (abnormal enlargement of the liver)
Infection
Injury
Osteitis (a general term for inflammation of bone)

What are the common drug interactions of Tobradex and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)

10-19:

Corneal exfoliation (removal of the oldest dead cells of outer most layer of cornea)

20-29:

n/a

30-39:

Pain
Abortion (termination of pregnancy)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Chest tightness
Complications of maternal exposure to therapeutic drugs
Depression
Drug dependence

40-49:

Conjunctival hyperaemia (congestion of conjunctival vessels)
Eye inflammation
Hypertension (high blood pressure)
Hypopyon (pus in the eye)
Metastases to heart (cancer spreads to heart)
Metastases to lung (cancer spreads to lung)
Neuropathy peripheral (surface nerve damage)
Pneumonia
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Ulcerative keratitis (ulcerative inflammation of the cornea)

50-59:

Coronary artery stenosis (narrowing of coronary artery)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Cytomegalovirus hepatitis (virus infection of liver)
Decreased activity
Deformity (disfigurement)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dry mouth
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Electrocardiogram poor r-wave progression

60+:

Pain
Injury
Fistula (an abnormal connection or passageway between two)
Gingivitis (inflammation of gums)
Hepatomegaly (abnormal enlargement of the liver)
Infection
Osteitis (a general term for inflammation of bone)
Skin lesion
Swelling
Tooth abscess (pus formation in tooth)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 9 people, 13.64%
High Blood Pressure: 5 people, 7.58%
Conjunctivitis (pink eye): 5 people, 7.58%

* Approximation only. Some reports may have incomplete information.

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