Tobramycin sulfate and Augmentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tobramycin sulfate (tobramycin sulfate) and Augmentin (amoxicillin; clavulanate potassium). Common drug interactions include fall among females and hepatic failure among males.

The phase IV clinical study analyzes what interactions people have when they take Tobramycin sulfate and Augmentin. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Tobramycin sulfate?

Tobramycin sulfate has active ingredients of tobramycin sulfate. eHealthMe is studying from 581 Tobramycin sulfate users. Check the latest studies of Tobramycin sulfate.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.



On Jul, 23, 2026

21 people who take Tobramycin sulfate and Augmentin together, and have interactions are studied.

Tobramycin sulfate and Augmentin drug interactions.

What are the common drug interactions of Tobramycin Sulfate and Augmentin, by gender? *:

female:

  1. Fall
  2. Activities of daily living impaired
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Arthropathy
  5. Asthenia (weakness)
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Dehydration (dryness resulting from the removal of water)
  8. Diarrhoea
  9. Essential hypertension (primary hypertension)
  10. Fatigue (feeling of tiredness)

male:

  1. Hepatic failure (liver failure)
  2. Large intestinal haemorrhage (bleeding in large intestine)
  3. Fungal sepsis (whole body infection by fungus)
  4. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  5. Tumour haemorrhage (bleeding from tumour)
  6. Post procedural complication
  7. Aspergillosis (an infection caused by a fungus called aspergillus)
  8. Bradycardia (abnormally slow heart action)
  9. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Tobramycin Sulfate and Augmentin, by age (0-1 to 60+)? *:

0-1:

  1. Bradycardia (abnormally slow heart action)
  2. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  3. Hepatic failure (liver failure)
  4. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  5. Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Ascites (accumulation of fluid in the abdominal cavity)
  8. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  9. Enteritis necroticans (fatal type of food poisoning caused by a -toxin of clostridium perfringens toxins)
  10. Gastroenteritis (inflammation of stomach and intestine)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  2. Arthropathy
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Essential hypertension (primary hypertension)
  5. Fatigue (feeling of tiredness)
  6. Hot flush (sudden feelings of heat)
  7. Hyperlipidaemia (presence of excess lipids in the blood)
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  9. Muscle spasms (muscle contraction)
  10. Myalgia (muscle pain)

60+:

  1. Hepatic failure (liver failure)
  2. Large intestinal haemorrhage (bleeding in large intestine)
  3. Fungal sepsis (whole body infection by fungus)
  4. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  5. Tumour haemorrhage (bleeding from tumour)
  6. Post procedural complication
  7. Aspergillosis (an infection caused by a fungus called aspergillus)
  8. Colon neoplasm (cancer from uncontrolled cell growth in the colon or rectum)
  9. Fall
  10. Oxygen saturation decreased

What are the existing conditions these people have? *

  1. Sedation: 14 people, 66.67%
  2. Infection: 14 people, 66.67%
  3. High Blood Pressure: 14 people, 66.67%
  4. Fungal Infection: 14 people, 66.67%
  5. Lung Infection: 4 people, 19.05%
  6. Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Tobramycin sulfate and Augmentin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tobramycin sulfate and Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tobramycin sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tobramycin sulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Augmentin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tobramycin sulfate and amoxicillin; clavulanate potassium (the active ingredients of Tobramycin sulfate and Augmentin, respectively), and Tobramycin sulfate and Augmentin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: