Tobramycin and Rabeprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tobramycin (tobramycin) and Rabeprazole (rabeprazole sodium). Common drug interactions include pyrexia among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Tobramycin and Rabeprazole. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Tobramycin?

Tobramycin has active ingredients of tobramycin. It is often used in cystic fibrosis. eHealthMe is studying from 3,579 Tobramycin users. Check the latest studies of Tobramycin.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.



On Jul, 09, 2026

15 people who take Tobramycin and Rabeprazole together, and have interactions are studied.

Tobramycin and Rabeprazole drug interactions.

What are the common drug interactions of Tobramycin and Rabeprazole, by gender? *:

female:

  1. Pyrexia (fever)
  2. Vomiting
  3. Infusion site bruising
  4. Infusion site pruritus (severe itching at infusion site)
  5. Blood cholesterol increased
  6. Rosacea (a skin condition that causes facial redness)
  7. Infection
  8. Infusion related reaction
  9. Nausea (feeling of having an urge to vomit)
  10. Respiratory tract infection

male:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Hypotension (abnormally low blood pressure)
  3. Productive cough
  4. Decreased appetite
  5. Mass
  6. Pain
  7. Prostate cancer
  8. C-reactive protein increased
  9. Dacryocystitis (inflammation of the lacrimal sac causing obstruction of the tube draining tears into the nose)
  10. Myalgia (muscle pain)

What are the common drug interactions of Tobramycin and Rabeprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Breath sounds
  2. Cerebral haemorrhage (bleeding within the brain)
  3. Confusional state
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Hypotension (abnormally low blood pressure)
  6. Nystagmus (a condition of involuntary eye movement)
  7. Productive cough
  8. Pyrexia (fever)
  9. Coma (state of unconsciousness lasting more than six hours)
  10. Quadriplegia (a four limb paralysis)

50-59:

  1. Pneumonia
  2. Pyrexia (fever)
  3. Rash
  4. Renal impairment (severely reduced kidney function)
  5. Blood cholesterol increased
  6. Blood creatine phosphokinase increased
  7. C-reactive protein increased
  8. Dacryocystitis (inflammation of the lacrimal sac causing obstruction of the tube draining tears into the nose)
  9. Myalgia (muscle pain)
  10. Pingueculitis (disorder of eye)

60+:

  1. Infection
  2. Sinusitis (inflammation of sinus)
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Hypotension (abnormally low blood pressure)
  5. Mass
  6. Pain
  7. Prostate cancer
  8. Infusion site bruising
  9. Infusion site pruritus (severe itching at infusion site)
  10. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

What are the existing conditions these people have? *

  1. Immune System Disorder: 6 people, 40.00%
  2. Immunodeficiency Common Variable: 6 people, 40.00%
  3. Psoriasis (immune-mediated disease that affects the skin): 4 people, 26.67%
  4. High Blood Pressure: 4 people, 26.67%
  5. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 20.00%
  6. Asthma: 3 people, 20.00%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 20.00%
  8. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 3 people, 20.00%
  9. Acidosis (build-up of carbon dioxide in the blood): 3 people, 20.00%
  10. Sputum Purulent: 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Tobramycin and Rabeprazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tobramycin and Rabeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tobramycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rabeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tobramycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rabeprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tobramycin and rabeprazole sodium (the active ingredients of Tobramycin and Rabeprazole, respectively), and Tobramycin and Rabeprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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