Toprol-xl and Lucentis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Toprol-xl (metoprolol succinate) and Lucentis (ranibizumab). Common drug interactions include lip pain among females and visual acuity reduced among males.

The phase IV clinical study analyzes what interactions people have when they take Toprol-xl and Lucentis. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Toprol-xl?

Toprol-xl has active ingredients of metoprolol succinate. It is often used in high blood pressure. eHealthMe is studying from 40,636 Toprol-xl users. Check the latest studies of Toprol-xl.

What is Lucentis?

Lucentis has active ingredients of ranibizumab. It is often used in macular degeneration. eHealthMe is studying from 25,647 Lucentis users. Check the latest studies of Lucentis.



On Jul, 12, 2026

39 people who take Toprol-xl and Lucentis together, and have interactions are studied.

Toprol-xl and Lucentis drug interactions.

What are the common drug interactions of Toprol-Xl and Lucentis, by gender? *:

female:

  1. Lip pain
  2. Lip swelling
  3. Rash
  4. Upper respiratory tract infection
  5. Burning sensation
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Contusion (a type of hematoma of tissue in which capillaries)
  8. Eye haemorrhage (bleeding in the eye)
  9. Eye pain
  10. Headache (pain in head)

male:

  1. Visual acuity reduced (reduced clearness of vision)
  2. Intraocular pressure increased
  3. Pneumonia
  4. Visual impairment
  5. Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)

What are the common drug interactions of Toprol-Xl and Lucentis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Intraocular pressure increased
  2. Lip pain
  3. Headache (pain in head)
  4. Upper respiratory tract infection
  5. Visual impairment
  6. Vitreous floaters (spots before the eyes)
  7. White blood cell count increased
  8. Bone pain
  9. Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
  10. Dizziness

What are the existing conditions these people have? *

  1. Stress And Anxiety: 2 people, 5.13%
  2. Retinal Vessel Occlusion (a blockage in one of the small arteries): 2 people, 5.13%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.13%
  4. High Blood Cholesterol: 2 people, 5.13%
  5. Diabetes: 2 people, 5.13%
  6. Cardiac Disorder: 2 people, 5.13%
  7. Bone Disorder: 2 people, 5.13%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Toprol-xl and Lucentis?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Toprol-xl and Lucentis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Toprol-xl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lucentis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Toprol-xl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lucentis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on metoprolol succinate and ranibizumab (the active ingredients of Toprol-xl and Lucentis, respectively), and Toprol-xl and Lucentis (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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