Toradol and Leflunomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Toradol (ketorolac tromethamine) and Leflunomide (leflunomide). Common drug interactions include speech disorder among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Toradol and Leflunomide. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Toradol?

Toradol has active ingredients of ketorolac tromethamine. It is often used in pain. eHealthMe is studying from 9,231 Toradol users. Check the latest studies of Toradol.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

75 people who take Toradol and Leflunomide together, and have interactions are studied.

Toradol and Leflunomide drug interactions.

What are the common drug interactions of Toradol and Leflunomide, by gender? *:

female:

Speech disorder
C-reactive protein increased
Confusional state
Cystitis (inflammation of the wall of the bladder)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dysuria (painful or difficult urination)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Incoherent (talking in a confused and unclear way)
Memory impairment
Micturition urgency (urgency to pass the urine)

male:

Drug ineffective
White blood cell count decreased
Drug intolerance (drug sensitivity)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Leukopenia (less number of white blood cells in blood)
White blood cell count increased

What are the common drug interactions of Toradol and Leflunomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chills (felling of cold)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Dizziness
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Ileitis (inflammation of the ileum)
Influenza like illness
Irritable bowel syndrome
Night sweats (sweating in night)
Urinary tract infection

30-39:

Fatigue (feeling of tiredness)
Rash
Abdominal discomfort
Asthma
Cough
Influenza
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Rhinorrhoea (watery mucus discharge from the nose)

40-49:

Anaphylactic reaction (serious allergic reaction)
Ankylosing spondylitis (type of arthritis affecting the spine)
Arthropathy
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug hypersensitivity
Drug ineffective
Drug intolerance (drug sensitivity)
Dyspnoea (difficult or laboured respiration)
Gait disturbance

50-59:

Neck pain
Oropharyngeal pain
Pneumonia
Psoriasis (immune-mediated disease that affects the skin)
Rash
Rheumatoid factor positive
Speech disorder
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Arthropathy

60+:

Dizziness
Fatigue (feeling of tiredness)
Memory impairment
Micturition urgency (urgency to pass the urine)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Oedema peripheral (superficial swelling)
Urinary tract disorder
Speech disorder
Polyarthritis (arthritis which involves 5 or more joints simultaneously)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 22 people, 29.33%
Stress And Anxiety: 17 people, 22.67%
Cardiac Disorder: 16 people, 21.33%
Stable Angina (a constant chest pain): 15 people, 20.00%
Back Pain: 15 people, 20.00%
Seronegative Arthritis (a joint disease negative for rheumatoid arthritis): 12 people, 16.00%
Rickets (softening of bones): 12 people, 16.00%
Joint Effusion (presence of extra fluid in joint covering): 12 people, 16.00%
Sleep Disorder: 11 people, 14.67%
Muscle Spasms (muscle contraction): 9 people, 12.00%

* Approximation only. Some reports may have incomplete information.

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