Toradol and Macrodantin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Toradol (ketorolac tromethamine) and Macrodantin (nitrofurantoin, macrocrystalline). Common drug interactions include hypoglycaemia among females and actinic keratosis among males.

The phase IV clinical study analyzes what interactions people have when they take Toradol and Macrodantin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Toradol?

Toradol has active ingredients of ketorolac tromethamine. It is often used in pain. eHealthMe is studying from 9,230 Toradol users. Check the latest studies of Toradol.

What is Macrodantin?

Macrodantin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 3,755 Macrodantin users. Check the latest studies of Macrodantin.

On Aug, 06, 2026

14 people who take Toradol and Macrodantin together, and have interactions are studied.

Toradol and Macrodantin drug interactions.

What are the common drug interactions of Toradol and Macrodantin, by gender? *:

female:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Injury
International normalised ratio increased
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Sudden cardiac death
Adjustment disorder
Brain neoplasm (tumour of brain)
Candidiasis (candidiasis or thrush is a fungal infection)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

male:

Actinic keratosis (skin disease due to sun exposure)
Alcohol abuse
Atrial tachycardia (rhythm disturbance that arises in the atria)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Bladder outlet obstruction (urological condition where the urine flow from the urinary bladder through the urethra is impeded)
Blepharitis (chronic inflammation of the eyelid)
Blood pressure decreased
Breath sounds
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the common drug interactions of Toradol and Macrodantin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Adjustment disorder
Brain neoplasm (tumour of brain)
Candidiasis (candidiasis or thrush is a fungal infection)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Constipation
Dependent personality disorder
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug abuse
Dysthymic disorder (mild chronic depression disorder)
Dysuria (painful or difficult urination)

40-49:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)

50-59:

Asthma
Atrial tachycardia (rhythm disturbance that arises in the atria)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Carotid artery stenosis (narrowing of carotid artery)
Diarrhoea
Drug hypersensitivity
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypertension (high blood pressure)
Hypoxia (low oxygen in tissues)

60+:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Actinic keratosis (skin disease due to sun exposure)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Atrial tachycardia (rhythm disturbance that arises in the atria)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Bladder outlet obstruction (urological condition where the urine flow from the urinary bladder through the urethra is impeded)
Blepharitis (chronic inflammation of the eyelid)
Blood pressure decreased
Breath sounds

What are the existing conditions these people have? *

Diabetes: 2 people, 14.29%
Stress And Anxiety: 1 person, 7.14%
Migraine (headache): 1 person, 7.14%
Insomnia (sleeplessness): 1 person, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.14%
Headache (pain in head): 1 person, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%
Dizziness: 1 person, 7.14%
Depression: 1 person, 7.14%
Cardiomyopathy (weakening of the heart muscle): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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