Toradol and Restasis drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Toradol (ketorolac tromethamine) and Restasis (cyclosporine). Common drug interactions include adrenal insufficiency among females and abscess neck among males.
The phase IV clinical study analyzes what interactions people have when they take Toradol and Restasis. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Toradol?
Toradol has active ingredients of ketorolac tromethamine. It is often used in pain. eHealthMe is studying from 9,230 Toradol users. Check the latest studies of Toradol.
What is Restasis?
Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.
26 people who take Toradol and Restasis together, and have interactions are studied.

What are the common drug interactions of Toradol and Restasis, by gender? *:
female:
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Anaemia of chronic disease
- Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
- Arteriovenous fistula site complication
- Atelectasis (partial or complete collapse of the lung)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bone disorder
- Candidiasis (candidiasis or thrush is a fungal infection)
- Cardiac arrest
- Cardiac disorder
male:
- Abscess neck (neck abscesses)
- Addison's disease (addison's disease, a hormonal disorder disease)
- Arthralgia (joint pain)
- Atelectasis (partial or complete collapse of the lung)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bone disorder
- Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
- Breast haematoma (blood-filled swelling in the breast)
- Cardiac arrest
- Cardiac disorder
What are the common drug interactions of Toradol and Restasis, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Injury
30-39:
- Blindness transient (sudden loss of vision)
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Visual field defect
- Dyslexia (disorders that involve difficulty in learning to read or interpret words, letters, and other symbols)
40-49:
- Muscle spasms (muscle contraction)
- Neurilemmoma benign (a non cancer tumour that typically grows on the myelin sheath of nerves in the head or neck)
- Somnambulism (sleep walking)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Hypokalaemia (low potassium)
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
50-59:
- Atelectasis (partial or complete collapse of the lung)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bone disorder
- Candidiasis (candidiasis or thrush is a fungal infection)
- Cardiac arrest
- Cardiac disorder
- Cardiac failure congestive
- Cardiomegaly (increased size of heart than normal)
- Cardiovascular disorder (heart diseases)
- Cataract (clouding of the lens inside the eye)
60+:
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Aortic dilatation
- Arrhythmia (irregular heartbeat)
- Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
- Arteriovenous fistula site complication
- Arthralgia (joint pain)
- Atelectasis (partial or complete collapse of the lung)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bone disorder
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 10 people, 38.46%
- Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 10 people, 38.46%
- Nausea (feeling of having an urge to vomit): 6 people, 23.08%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 23.08%
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 5 people, 19.23%
- Insomnia (sleeplessness): 3 people, 11.54%
- Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 11.54%
- Itching: 3 people, 11.54%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.54%
- High Blood Pressure: 3 people, 11.54%
* Approximation only. Some reports may have incomplete information.
Do you take Toradol and Restasis?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Toradol and Restasis:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Toradol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Restasis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Toradol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Restasis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on ketorolac tromethamine and cyclosporine (the active ingredients of Toradol and Restasis, respectively), and Toradol and Restasis (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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