Toradol and Zyvox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Toradol (ketorolac tromethamine) and Zyvox (linezolid). Common drug interactions include cardiac arrest among females and abscess limb among males.

The phase IV clinical study analyzes what interactions people have when they take Toradol and Zyvox. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Toradol?

Toradol has active ingredients of ketorolac tromethamine. It is often used in pain. eHealthMe is studying from 9,230 Toradol users. Check the latest studies of Toradol.

What is Zyvox?

Zyvox has active ingredients of linezolid. It is often used in mrsa infection. eHealthMe is studying from 9,399 Zyvox users. Check the latest studies of Zyvox.



On Jul, 18, 2026

12 people who take Toradol and Zyvox together, and have interactions are studied.

Toradol and Zyvox drug interactions.

What are the common drug interactions of Toradol and Zyvox, by gender? *:

female:

  1. Cardiac arrest
  2. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
  3. Nausea (feeling of having an urge to vomit)
  4. Vomiting
  5. Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
  6. Blood pressure decreased
  7. Drug ineffective
  8. Erythema (redness of the skin)
  9. Tendonitis (a condition that causes pain and swelling of tendons)
  10. Anaemia haemolytic autoimmune (a condition in which the immune system attacks the red blood cells, resulting in fewer of these oxygen-transporting cells)

male:

  1. Abscess limb (limb infection)
  2. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  3. Injection site pain
  4. Injection site swelling
  5. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  6. Joint effusion (presence of extra fluid in joint covering)
  7. Large intestinal ulcer
  8. Livedo reticularis (a lace-like purplish discoloration of the skin)
  9. Localised intraabdominal fluid collection (collection of fluid in abdomen in single site)
  10. Multi-organ failure (multisystem organ failure)

What are the common drug interactions of Toradol and Zyvox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)

20-29:

  1. Localised intraabdominal fluid collection (collection of fluid in abdomen in single site)

30-39:

  1. Chronic kidney disease
  2. Hyperkalaemia (damage to or disease of the kidney)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Renal failure (kidney dysfunction)
  6. Renal injury (kidney injury)
  7. Renal ischaemia (lack of blood supply to kidney)
  8. Renal tubular necrosis (death of kidney tubules)
  9. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

40-49:

n/a

50-59:

  1. International normalised ratio increased

60+:

  1. Cardiac arrest
  2. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
  3. Drug hypersensitivity
  4. Generalised oedema (swelling all over the body)
  5. Hypotension (abnormally low blood pressure)
  6. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  7. Large intestinal ulcer
  8. Livedo reticularis (a lace-like purplish discoloration of the skin)
  9. Multi-organ failure (multisystem organ failure)
  10. Myelitis transverse (a neurological condition consisting of an inflammatory process of the spinal cord)

What are the existing conditions these people have? *

  1. Nausea And Vomiting: 3 people, 25.00%
  2. Body Temperature Increased: 2 people, 16.67%
  3. Nausea (feeling of having an urge to vomit): 2 people, 16.67%
  4. Infection: 2 people, 16.67%
  5. Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls): 1 person, 8.33%
  6. Dry Eyes (lack of adequate tears): 1 person, 8.33%
  7. Agitation (state of anxiety or nervous excitement): 1 person, 8.33%
  8. Cellulitis (infection under the skin): 1 person, 8.33%
  9. Constipation: 1 person, 8.33%
  10. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Toradol and Zyvox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Toradol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zyvox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Toradol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyvox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ketorolac tromethamine and linezolid (the active ingredients of Toradol and Zyvox, respectively), and Toradol and Zyvox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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