Torisel and Lipitor drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Torisel (temsirolimus) and Lipitor (atorvastatin calcium). Common drug interactions include acute myocardial infarction among females and pleural effusion among males.
The phase IV clinical study analyzes what interactions people have when they take Torisel and Lipitor. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Torisel?
Torisel has active ingredients of temsirolimus. eHealthMe is studying from 3,205 Torisel users. Check the latest studies of Torisel.
What is Lipitor?
Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,047 Lipitor users. Check the latest studies of Lipitor.
44 people who take Torisel and Lipitor together, and have interactions are studied.

What are the common drug interactions of Torisel and Lipitor, by gender? *:
female:
- Acute myocardial infarction (acute heart attack)
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood glucose increased
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Lymphocyte count decreased
- Anticonvulsant drug level below therapeutic
- Blood creatinine increased
- Blood potassium decreased
- Chest pain
male:
- Pleural effusion (water on the lungs)
- Oedema peripheral (superficial swelling)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Scrotal oedema (swelling of scrotum)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Pericardial effusion (fluid around the heart)
- Anaemia (lack of blood)
- Ileus (a painful obstruction of the ileum or other part of the intestine)
- Interstitial lung disease
- Joint swelling
What are the common drug interactions of Torisel and Lipitor, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Anaemia (lack of blood)
- Interstitial lung disease
- Pain
- Pneumonia
- Renal failure (kidney dysfunction)
- Alveolar osteitis (complication of wound healing following extraction of a tooth)
- Bone disorder
- Dehydration (dryness resulting from the removal of water)
- Hyperglycaemia (high blood sugar)
- Lung neoplasm (tumour of lung)
60+:
- Acute myocardial infarction (acute heart attack)
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
- Dysarthria (speech disorder)
- Lymphocyte count decreased
- Nail disorder (disease of nail)
- Nystagmus (a condition of involuntary eye movement)
- Platelet count decreased
- Scrotal oedema (swelling of scrotum)
- Blood creatinine increased
- Blood potassium decreased
What are the existing conditions these people have? *
- Renal Cell Carcinoma (a kidney cancer): 23 people, 52.27%
- High Blood Pressure: 8 people, 18.18%
- Nausea (feeling of having an urge to vomit): 7 people, 15.91%
- Prostate Cancer: 6 people, 13.64%
- Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 5 people, 11.36%
- Pain: 4 people, 9.09%
- Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 4 people, 9.09%
- Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 9.09%
- Cervicobrachial Syndrome (pain in neck and arm with changing location): 4 people, 9.09%
- Metastases To Bone (cancer spreads to bone): 3 people, 6.82%
* Approximation only. Some reports may have incomplete information.
Do you take Torisel and Lipitor?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Torisel and Lipitor:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Torisel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lipitor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Torisel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lipitor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Herrin MA, Rubinstein JC, Christison-Lagay ER, "Temsirolimus therapy and small bowel perforation in a pediatric patient with Clostridium septicum bacteremia", Journal of Pediatric Surgery Case Reports, 2015 Aug .
- Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
- Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
- Herrin MA, Rubinstein JC, Christison-Lagay ER, "Temsirolimus therapy and small bowel perforation in a pediatric patient with Clostridium septicum bacteremia", Journal of Pediatric Surgery Case Reports, 2015 Aug .
- Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
- Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on temsirolimus and atorvastatin calcium (the active ingredients of Torisel and Lipitor, respectively), and Torisel and Lipitor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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