Torisel and Oxycodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Torisel (temsirolimus) and Oxycodone (oxycodone hydrochloride). Common drug interactions include pneumonia among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Torisel and Oxycodone. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Torisel?

Torisel has active ingredients of temsirolimus. eHealthMe is studying from 3,205 Torisel users. Check the latest studies of Torisel.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.



On Feb, 19, 2026

42 people who take Torisel and Oxycodone together, and have interactions are studied.

Torisel and Oxycodone drug interactions.

What are the common drug interactions of Torisel and Oxycodone, by gender? *:

female:

  1. Pneumonia
  2. Rash
  3. Abdominal distension
  4. Abdominal mass (localized enlargement or swelling in the human abdomen)
  5. Abdominal pain
  6. Abscess intestinal (collections of pus-intestinal)
  7. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  8. Anaemia (lack of blood)
  9. Anticonvulsant drug level below therapeutic
  10. Aortic arteriosclerosis (hardening of the aortic arteries)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Dehydration (dryness resulting from the removal of water)
  3. Pain in extremity
  4. Rash generalised (rash on most of body parts)
  5. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  6. Aortic calcification (aortic calcification sign of heart valve disease)
  7. Blood alkaline phosphatase increased
  8. Blood glucose increased
  9. Cardiomegaly (increased size of heart than normal)
  10. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)

What are the common drug interactions of Torisel and Oxycodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Dehydration (dryness resulting from the removal of water)
  2. Diarrhoea
  3. Drug ineffective

10-19:

  1. Antinuclear antibody positive
  2. Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
  3. Body height decreased
  4. Dehydration (dryness resulting from the removal of water)
  5. Drug ineffective
  6. Haemorrhage intracranial (bleeding within the skull)
  7. Hydrocephalus (water on the brain)
  8. Hypertension (high blood pressure)
  9. Insomnia (sleeplessness)
  10. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

20-29:

  1. Disease progression
  2. Renal cell carcinoma (a kidney cancer)
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Small intestinal obstruction (blockage in small intestine)

30-39:

  1. Chest discomfort
  2. Flushing (the warm, red condition of human skin)
  3. Hypersensitivity
  4. Pneumonia
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Septic shock (shock due to blood infection)

40-49:

  1. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
  2. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  3. Platelet count decreased
  4. White blood cell count decreased

50-59:

  1. Chest discomfort
  2. Dehydration (dryness resulting from the removal of water)
  3. Feeling hot
  4. Hypersensitivity
  5. Rash erythematous (redness of the skin)
  6. Skin exfoliation (removal of the oldest dead skin cells)
  7. Death
  8. Dizziness
  9. Erythema (redness of the skin)
  10. Fatigue (feeling of tiredness)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Pleural effusion (water on the lungs)
  3. Cardiomegaly (increased size of heart than normal)
  4. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  5. Generalised oedema (swelling all over the body)
  6. Hypertension (high blood pressure)
  7. Lymphadenopathy (disease or enlargement of lymph nodes)
  8. Pericardial effusion (fluid around the heart)
  9. Pericardial fibrosis (mass or abnormal tissue in the heart and surrounding areas)
  10. Pulmonary hypertension (increase in blood pressure in the lung artery)

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 21 people, 50.00%
  2. Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 5 people, 11.90%
  3. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 5 people, 11.90%
  4. Constipation: 5 people, 11.90%
  5. Neuralgia (pain in one or more nerves): 3 people, 7.14%
  6. Nausea (feeling of having an urge to vomit): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Torisel and Oxycodone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Torisel and Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Torisel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Torisel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on temsirolimus and oxycodone hydrochloride (the active ingredients of Torisel and Oxycodone, respectively), and Torisel and Oxycodone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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