Tpn and Multivitamin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tpn (niacinamide; pyridoxine hydrochloride; tyrosine) and Multivitamin (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include hypokalaemia among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Tpn and Multivitamin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Tpn?

Tpn has active ingredients of niacinamide; pyridoxine hydrochloride; tyrosine. eHealthMe is studying from 1,581 Tpn users. Check the latest studies of Tpn.

What is Multivitamin?

Multivitamin has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 83,597 Multivitamin users. Check the latest studies of Multivitamin.

On Jul, 08, 2026

32 people who take Tpn and Multivitamin together, and have interactions are studied.

What are the common drug interactions of Tpn and Multivitamin, by gender? *:

female:

Hypokalaemia (low potassium)
Bacteraemia (presence of bacteria in the blood)
Nausea (feeling of having an urge to vomit)
Streptococcal infection
Abdominal pain
Dehydration (dryness resulting from the removal of water)
Pyrexia (fever)
Hepatic atrophy (liver is decreased in size)
Abdominal pain upper
Fatigue (feeling of tiredness)

male:

Dehydration (dryness resulting from the removal of water)
Intestinal perforation (complete penetration of the wall of the intestine)
Eating disorder
Faeces discoloured
Fatigue (feeling of tiredness)
Hepatic failure (liver failure)
Metastases to liver (cancer spreads to liver)
Nasopharyngitis (inflammation of the nasopharynx)
Oropharyngeal pain
Pancreatic mass

What are the common drug interactions of Tpn and Multivitamin, by age (0-1 to 60+)? *:

0-1:

Anaphylactic reaction (serious allergic reaction)

2-9:

n/a

10-19:

Weight increased
Abdominal discomfort
Abdominal pain upper
Blood pressure decreased
Cough
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Eating disorder
Faeces discoloured
Fatigue (feeling of tiredness)

20-29:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Transaminases increased

30-39:

n/a

40-49:

Hypokalaemia (low potassium)
Bacteraemia (presence of bacteria in the blood)
Streptococcal infection
Pyrexia (fever)
Hepatic atrophy (liver is decreased in size)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Abdominal distension
Nausea (feeling of having an urge to vomit)
Abdominal pain
Abdominal pain upper

50-59:

Dehydration (dryness resulting from the removal of water)
Intestinal perforation (complete penetration of the wall of the intestine)
Abdominal pain
Anaemia (lack of blood)
Asthenia (weakness)
Bacteraemia (presence of bacteria in the blood)
Decreased appetite
Device related infection
Failure to thrive (inadequate weight gain and physical growth in children)
Hospitalisation

60+:

Abdominal pain
Blood uric acid decreased
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypophysitis (inflammation of the pituitary gland)
Hypotension (abnormally low blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Impaired gastric emptying
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 23 people, 71.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 28.12%
Pain: 9 people, 28.12%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 4 people, 12.50%
Abdominal Pain: 3 people, 9.38%
Migraine (headache): 2 people, 6.25%
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 2 people, 6.25%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 6.25%
Liver Disorder (liver diseases): 2 people, 6.25%
Sedation: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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