Tpn and Zolpidem drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tpn (niacinamide; pyridoxine hydrochloride; tyrosine) and Zolpidem (zolpidem tartrate). Common drug interactions include abdominal pain upper among females and hepatic enzyme increased among males.
The phase IV clinical study analyzes what interactions people have when they take Tpn and Zolpidem. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Tpn?
Tpn has active ingredients of niacinamide; pyridoxine hydrochloride; tyrosine. eHealthMe is studying from 1,581 Tpn users. Check the latest studies of Tpn.
What is Zolpidem?
Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.
15 people who take Tpn and Zolpidem together, and have interactions are studied.

What are the common drug interactions of Tpn and Zolpidem, by gender? *:
female:
- Abdominal pain upper
- Anuria (failure of the kidneys to produce urine)
- Decreased appetite
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Abdominal pain
- Ankle fracture
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Diarrhoea
- Dyspepsia (indigestion)
male:
- Hepatic enzyme increased
- Hepatic steatosis (fatty liver disease)
- Enteritis (inflammation of the small intestine)
- Neutropenia (an abnormally low number of neutrophils)
- Sepsis (a severe blood infection that can lead to organ failure and death)
What are the common drug interactions of Tpn and Zolpidem, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain upper
- Ankle fracture
- Anuria (failure of the kidneys to produce urine)
- Decreased appetite
- Diarrhoea
- Dyspepsia (indigestion)
- Fatigue (feeling of tiredness)
- Feeding disorder (when children refuse to eat certain food groups)
- Frequent bowel movements
- Gait disturbance
50-59:
- Enteritis (inflammation of the small intestine)
- Hypotension (abnormally low blood pressure)
- Neutropenia (an abnormally low number of neutrophils)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Wheezing (a high-pitched whistling sound made while you breath)
- Hypoxia (low oxygen in tissues)
- Pleural effusion (water on the lungs)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Dyspnoea (difficult or laboured respiration)
60+:
- Hepatic enzyme increased
- Hepatic steatosis (fatty liver disease)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Systemic candida (whole body fungal infection)
What are the existing conditions these people have? *
- Pain: 7 people, 46.67%
- Fever: 6 people, 40.00%
- Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 33.33%
- Fainting (loss of consciousness and postural tone): 4 people, 26.67%
- Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 4 people, 26.67%
- Constipation: 4 people, 26.67%
- Pleural Effusion (water on the lungs): 4 people, 26.67%
- Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 4 people, 26.67%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 26.67%
- Spinal Osteoarthritis (joint cartilage loss in spine): 4 people, 26.67%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tpn and Zolpidem:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tpn:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zolpidem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tpn and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zolpidem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on niacinamide; pyridoxine hydrochloride; tyrosine and zolpidem tartrate (the active ingredients of Tpn and Zolpidem, respectively), and Tpn and Zolpidem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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