Tramadol hydrochloride and Adalat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tramadol hydrochloride (tramadol hydrochloride) and Adalat (nifedipine). Common drug interactions include pleural effusion among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Tramadol hydrochloride and Adalat. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Tramadol hydrochloride?

Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 40,749 Tramadol hydrochloride users. Check the latest studies of Tramadol hydrochloride.

What is Adalat?

Adalat has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 20,940 Adalat users. Check the latest studies of Adalat.

On Jul, 13, 2026

29 people who take Tramadol hydrochloride and Adalat together, and have interactions are studied.

Tramadol hydrochloride and Adalat drug interactions.

What are the common drug interactions of Tramadol Hydrochloride and Adalat, by gender? *:

female:

Pleural effusion (water on the lungs)
Pneumonia
Rash macular (small, flat red spots)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Synovial cyst (cyst of joint filled with synovial fluid)
Thrombocytopenia (decrease of platelets in blood)
Visual impairment
Weight increased
Rash
Fatigue (feeling of tiredness)

male:

Asthenia (weakness)
Constipation
Haemoglobin decreased
Hepatic enzyme increased
Hepatic failure (liver failure)
Mediastinitis (inflammation of the tissues in the mid-chest)
Metastases to liver (cancer spreads to liver)
Osteonecrosis of jaw (death of bone of jaw)
Pain in jaw
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the common drug interactions of Tramadol Hydrochloride and Adalat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Hypotension (abnormally low blood pressure)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pericarditis (inflammation of the pericardium)

50-59:

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)

60+:

Rash
Anaemia (lack of blood)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Migraine (headache)
Oesophageal haemorrhage (bleeding from oesophagus)
Sinus headache (headache caused by sinus infections)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tension headache
Thyroid neoplasm (tumour of thyroid)
Tremor (trembling or shaking movements in one or more parts of your body)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 34.48%
Gastrointestinal Pain: 7 people, 24.14%
Urination - Excessive Volume: 4 people, 13.79%
Iron Deficiency: 3 people, 10.34%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 10.34%
Oedema (fluid collection in tissue): 3 people, 10.34%
Nausea (feeling of having an urge to vomit): 3 people, 10.34%
Left Ventricular Failure (left ventricle fails to contract forcefully): 3 people, 10.34%
Constipation: 3 people, 10.34%
Anaesthesia: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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