Tramadol and Anaprox ds drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tramadol (tramadol hydrochloride) and Anaprox ds (naproxen sodium). Common drug interactions include drug ineffective among females and asthenia among males.
The phase IV clinical study analyzes what interactions people have when they take Tramadol and Anaprox ds. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Tramadol?
Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 235,798 Tramadol users. Check the latest studies of Tramadol.
What is Anaprox ds?
Anaprox ds has active ingredients of naproxen sodium. eHealthMe is studying from 265 Anaprox ds users. Check the latest studies of Anaprox ds.
15 people who take Tramadol and Anaprox ds together, and have interactions are studied.

What are the common drug interactions of Tramadol and Anaprox Ds, by gender? *:
female:
- Drug ineffective
- Localised infection (infection at the single location)
- Back disorder
- Arthropathy
- Asthma
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Cystitis (inflammation of the wall of the bladder)
- Dizziness
- Drug hypersensitivity
male:
- Asthenia (weakness)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Injection site pain
- Sinusitis (inflammation of sinus)
- Dysarthria (speech disorder)
- Faecal incontinence (a lack of control over passing stool)
- Fall
- Gait disturbance
- Hallucination (an experience involving the perception of something not present)
- Urinary incontinence (inability to control the flow of urine and involuntary urination)
What are the common drug interactions of Tramadol and Anaprox Ds, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Drug ineffective
- Localised infection (infection at the single location)
- Arthropathy
- Back disorder
- Asthma
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
50-59:
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Back disorder
- Dizziness
- Drug hypersensitivity
- Fatigue (feeling of tiredness)
- Foot fracture
- Heart rate decreased
- Muscle spasms (muscle contraction)
- Nausea (feeling of having an urge to vomit)
- Road traffic accident
60+:
- Asthenia (weakness)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Injection site pain
- Sinusitis (inflammation of sinus)
- Dysarthria (speech disorder)
- Faecal incontinence (a lack of control over passing stool)
- Fall
- Gait disturbance
- Hallucination (an experience involving the perception of something not present)
- Urinary incontinence (inability to control the flow of urine and involuntary urination)
What are the existing conditions these people have? *
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 7 people, 46.67%
- Neuropathy Peripheral (surface nerve damage): 7 people, 46.67%
- Muscle Spasms (muscle contraction): 7 people, 46.67%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 13.33%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 13.33%
- Urinary Tract Infection: 1 person, 6.67%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 6.67%
- Joint Pain: 1 person, 6.67%
- Genital Rash (rash on sex organ): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Tramadol and Anaprox ds?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Tramadol (235,798 reports)
- Anaprox ds (265 reports)
Browse all drug interactions of Tramadol and Anaprox ds:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tramadol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Anaprox ds:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tramadol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Anaprox ds and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on tramadol hydrochloride and naproxen sodium (the active ingredients of Tramadol and Anaprox ds, respectively), and Tramadol and Anaprox ds (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Metrogel vs. Retin-A, side effect and effectiveness comparison - 9 seconds ago
- Drug interactions of Methadone Hydrochloride and Ceftazidime - 14 seconds ago
- Could Methotrexate cause Pneumocystis Carinii Infection? - 19 seconds ago
- Could Accupril cause Weight Fluctuation? - 27 seconds ago
- Drug interactions of Vitamin B6 and Loraz - 31 seconds ago
- Procardia vs. Amiloride Hydrochloride And Hydrochlorothiazide, side effect and effectiveness comparison - 38 seconds ago
- Drug interactions of Dulcolax and Fentanyl - 42 seconds ago
- Could Glimepiride cause Skin Abscess? - 54 seconds ago
- Could Fluphenazine cause Dyspnea Exacerbated? - 57 seconds ago
- Could Verapamil Hydrochloride cause Interstitial Lung Disease? - a minute ago