Tramadol and Avapro drug interactions - from FDA reports

Summary

Drug interactions are reported among people who take Tramadol and Avapro together. This study is created by eHealthMe based on reports of 302 people who take Tramadol and Avapro from FDA, and is updated regularly.



What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on tramadol hydrochloride and irbesartan (the active ingredients of Tramadol and Avapro, respectively), and Tramadol and Avapro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

What is Tramadol?

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 112,006 users)

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. (latest outcomes from Avapro 16,377 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.


On Feb, 27, 2019

302 people who take Tramadol, Avapro are studied.


Number of reports submitted per year:

Tramadol and Avapro drug interactions.

Most common drug interactions over time *:

< 1 month:
  1. Fall
  2. Drooling (drop saliva uncontrollably from the mouth)
  3. Eye rolling
  4. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  5. Radius fracture
  6. Vomiting
  7. Chest pain
  8. Dyskinesia (abnormality or impairment of voluntary movement)
  9. Dysphagia (condition in which swallowing is difficult or painful)
  10. Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
1 - 6 months:
  1. Blood uric acid increased
  2. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  3. Dyspepsia (indigestion)
  4. Electrocardiogram qt prolonged
  5. General physical health deterioration (weak health status)
  6. Haematotoxicity (toxins that destroy red blood cells)
  7. Hepatic enzyme increased
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Myalgia (muscle pain)
  10. Neutropenia (an abnormally low number of neutrophils)
6 - 12 months:
  1. Colitis (inflammation of colon)
  2. Constipation
  3. Diarrhoea
  4. Dyspepsia (indigestion)
  5. Hepatic steatosis (fatty liver disease)
  6. Hyperkalaemia (damage to or disease of the kidney)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  9. Night sweats (sweating in night)
  10. Pyrexia (fever)
1 - 2 years:
  1. Abdominal pain
  2. Acute sinusitis
  3. Alopecia (absence of hair from areas of the body)
  4. Anaemia (lack of blood)
  5. Arthropathy
  6. Asthma
  7. Blood alkaline phosphatase increased
  8. Breast mass
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
2 - 5 years:
  1. Migraine (headache)
  2. Myalgia (muscle pain)
  3. Mycobacterium avium complex infection
  4. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  5. Nausea (feeling of having an urge to vomit)
  6. Neck pain
  7. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  8. Neuropathy peripheral (surface nerve damage)
  9. Oedema (fluid collection in tissue)
  10. Oedema peripheral (superficial swelling)
5 - 10 years:
  1. Blood uric acid increased
  2. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  3. Anxiety
  4. Blood pressure fluctuation
  5. Chest discomfort
  6. Depression
  7. Drug hypersensitivity
  8. Dyspepsia (indigestion)
  9. Dyspnoea (difficult or laboured respiration)
  10. Electrocardiogram qt prolonged
10+ years:
  1. Blood uric acid increased
  2. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Dyspepsia (indigestion)
  5. Electrocardiogram qt prolonged
  6. General physical health deterioration (weak health status)
  7. Haematotoxicity (toxins that destroy red blood cells)
  8. Hepatic enzyme increased
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Neutropenia (an abnormally low number of neutrophils)
not specified:
  1. Dyspnoea (difficult or laboured respiration)
  2. Dizziness
  3. Nausea (feeling of having an urge to vomit)
  4. Headache (pain in head)
  5. Vomiting
  6. Fatigue (feeling of tiredness)
  7. Asthenia (weakness)
  8. Diarrhoea
  9. Weight decreased
  10. Pruritus (severe itching of the skin)

Most common drug interactions by gender *:

female:
  1. Headache (pain in head)
  2. Asthenia (weakness)
  3. Fall
  4. Pruritus (severe itching of the skin)
  5. Wheezing (a high-pitched whistling sound made while you breath)
  6. Dehydration (dryness resulting from the removal of water)
  7. Swollen tongue (swelling of tongue)
  8. Depression
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Constipation
male:
  1. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  2. Headache (pain in head)
  3. Fatigue (feeling of tiredness)
  4. Nausea (feeling of having an urge to vomit)
  5. Gait disturbance
  6. Hypotension (abnormally low blood pressure)
  7. Anaphylactic reaction (serious allergic reaction)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Anxiety
  10. Emotional distress

Most common drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:
  1. Dyspnoea (difficult or laboured respiration)
  2. Wheezing (a high-pitched whistling sound made while you breath)
  3. Status asthmaticus (a asthma attack not responds to regular medicines)
  4. Epistaxis (bleed from the nose)
  5. Pruritus (severe itching of the skin)
  6. Swollen tongue (swelling of tongue)
  7. Anaphylactic reaction (serious allergic reaction)
  8. Chest discomfort
  9. Cough
  10. Facial pain
40-49:
  1. Drooling (drop saliva uncontrollably from the mouth)
  2. Eye rolling
  3. Headache (pain in head)
  4. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  7. Hyperglycaemia (high blood sugar)
  8. Type 2 diabetes mellitus
  9. Abdominal infection
  10. Abdominal pain
50-59:
  1. Fatigue (feeling of tiredness)
  2. Injury
  3. Pyrexia (fever)
  4. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
  5. Urticaria (rash of round, red welts on the skin that itch intensely)
  6. Weight decreased
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Colitis (inflammation of colon)
  9. Constipation
  10. Diarrhoea
60+:
  1. Dizziness
  2. Nausea (feeling of having an urge to vomit)
  3. Dyspnoea (difficult or laboured respiration)
  4. Fall
  5. Arthralgia (joint pain)
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Blood uric acid increased
  8. Vision blurred
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Pain in extremity

* Approximation only. Some reports may have incomplete information.

Do you take Tramadol and Avapro?


You are not alone:




Related publications that referenced our studies

Related studies

Browse interactions by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Interactions between Tramadol and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Interactions between Avapro and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Tramadol and Avapro
a b c d e f g h i j k l m n o p q r s t u v w x y z

What would happen?

Predict new side effects and undetected conditions when you take Tramadol and Avapro



FDA reports used in this study


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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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